Results 121 to 130 of about 642,202 (317)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Separation of ions with the same charge to mass ratio from a collision experiment
Journal of the Serbian Chemical Society, 2000 Some atomic collision experiments lead to ions having identical q/m ratio, as well as average velocity, so that standard electric and magnetic analyzers are not able to identify them separately.
PIERRE DEFRANCE, DRAGOLJUB S. BELIC
doaj
, 1982 Oxygen dissociation curves of the whole blood of larvae and adults of the Southern Hemisphere lamprey Geotria australis have been determined between pH 6.8 and 8.2 at 5, 15 and 25 degrees C. 2. The P50's at temperatures of 5, 15 and 25 degrees C and a pH
Macey, D.J., Potter, I.C.
core
Metacognition and dissociation as mediators between childhood trauma and psychiatric symptoms
Background: Childhood trauma (CT) is a significant risk factor for the development of psychopathology, including maladaptive personality traits and psychiatric symptoms. CT has been shown to impact various psychological outcomes, including mood disorders
Giovanni Florio +4 more
core +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Theoretical models have proposed that inadequate caregiving environments undermine the development of adaptive regulation strategies at early stages and can lead children to inadequate regulation skills for coping with distress, such as dissociation ...
Pérez Rodríguez, Sandra +2 more
core +1 more source
Numerical simulation on the marine landslide due to gas hydrate dissociation
, 2017 Marine landslide due to gas hydrate dissociation is a kind of potential heavy hazards. Numerical simulation was processed to investigate the deformation landslide and effects of main factors on the critical scale of dissociation zone to induce marine ...
Lu L +4 more
core +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Dissociation and recovery in psychosis – an overview of the literature
Frontiers in PsychiatryBackgroundThe relationship between dissociation and recovery from psychosis is a new topic, which could attract the interest of the researchers in the field of dissociation due to its relevance to their daily clinical practice.
Claudia Calciu +8 more
doaj +1 more source