Results 121 to 130 of about 709,863 (314)

Metacognition and dissociation as mediators between childhood trauma and psychiatric symptoms

Background: Childhood trauma (CT) is a significant risk factor for the development of psychopathology, including maladaptive personality traits and psychiatric symptoms. CT has been shown to impact various psychological outcomes, including mood disorders
Giovanni Florio, Roberto Pedone, Anna Maria Barbarulo, Alessia Pappalardo, Benedetto Farina   +4 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Dissociation and recovery in psychosis – an overview of the literature

Frontiers in Psychiatry
BackgroundThe relationship between dissociation and recovery from psychosis is a new topic, which could attract the interest of the researchers in the field of dissociation due to its relevance to their daily clinical practice.
Claudia Calciu, Claudia Calciu, Rob Macpherson, Sui Yung Chen, Madalina Zlate, Rosemary C. King, Kerry J. Rees, Camelia Soponaru, Jackie Webb   +8 more
doaj   +1 more source

Dissociation, postraumática stress symptoms, emotional dysregulation, and invalidating environments as correlativo of ósea in borderline personality disorder patients

Theoretical models have proposed that inadequate caregiving environments undermine the development of adaptive regulation strategies at early stages and can lead children to inadequate regulation skills for coping with distress, such as dissociation ...
Pérez Rodríguez, Sandra, Lorca Alamar, Fátima, Marco Salvador, José Heliodoro   +2 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dissociation during positive situations

, 1995
p. 241-246Breaking from the traditional mode of dissociation research, this study examines the experience of dissociation during positive situations. Thirty-three of ninety (36.7%) randomly selected undergraduate students reported positive dissociative ...
Pica, Michael, Beere, Don
core   +1 more source

Numerical simulation on the marine landslide due to gas hydrate dissociation

, 2017
Marine landslide due to gas hydrate dissociation is a kind of potential heavy hazards. Numerical simulation was processed to investigate the deformation landslide and effects of main factors on the critical scale of dissociation zone to induce marine ...
Lu L, Chen XD, Lu, XB (reprint author), Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China., 鲁晓兵, 张旭辉   +4 more
core   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source