Results 61 to 70 of about 390,267 (298)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Chlorine nitrate in the atmosphere [PDF]

Atmospheric Chemistry and Physics, 2018
This review article compiles the characteristics of the gas chlorine nitrate and discusses its role in atmospheric chemistry. Chlorine nitrate is a reservoir of both stratospheric chlorine and nitrogen.
T. von Clarmann, S. Johansson
doaj   +1 more source

Solving the CH$_4^-$ riddle: the fundamental role of spin to explain metastable anionic methane

, 2019
When atoms or molecules exist in the form of stable negative ions, they play a crucial role in the gas phase chemistry. Determining the existence of such an ion, its internal energy and its stability are necessary prerequisites to analyze the role of ...
Hinojosa, Guillermo, Ramírez-Solís, Alejandro, Saint-Martin, Humberto, Viguè, Jacques   +3 more
core   +3 more sources

On the Energetics of the HCO$^+$ + C $\to$ CH$^+$ + CO Reaction and Some Astrochemical Implications [PDF]

, 2017
We explore the energetics of the titular reaction, which current astrochemical databases consider open at typical dense molecular (i.e., dark) cloud conditions.
Bhaskar, Roshan G., Savin, Daniel W., Urbain, Xavier, Vissapragada, Shreyas   +3 more
core   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Decisive role of nuclear quantum effects on surface mediated water dissociation at finite temperature

, 2017
Water molecules adsorbed on inorganic substrates play an important role in several technological applications. In the presence of light atoms in adsorbates, nuclear quantum effects (NQE) influence properties of these systems. In this work, we explore the
Davide Donadio, Johnson E., Mariana Rossi, Michele Ceriotti, Yair Litman   +4 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Formation of a 14‐Electron Intermediate in Iridium Catalysis through Reductive Elimination: Dissociation Is Rate Determining

ChemistryEurope
Oxidative addition and reductive elimination are fundamental processes in organometallic chemistry and are important in catalytic transformations involving C–H bonds.
Alice Spangenberg, Ola F. Wendt
doaj   +1 more source

Laboratory photo-chemistry of covalently bonded fluorene clusters: observation of an interesting PAH bowl-forming mechanism

, 2019
The fullerene C$_{60}$, one of the largest molecules identified in the interstellar medium (ISM), has been proposed to form top-down through the photo-chemical processing of large (more than 60 C-atoms) polycyclic aromatic hydrocarbon (PAH) molecules. In
Chen, Tao, Linnartz, Harold, Si, Yubing, Tielens, Alexander G. G. M., Zhang, Weiwei, Zhen, Junfeng   +5 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source