Dissociative anesthetics - Open Access .click

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Dissociation of Hypnotic-Anesthetic Actions of α2 Agonists From Cyclic AMP in the Rat

Pharmacology Biochemistry and Behavior, 1997
alpha 2 adrenergic agonists are used clinically for their anesthetic, analgesic, and sympatholytic actions in surgical patients. All alpha 2 adrenergic receptors, when activated by alpha 2-adrenergic agonists, are able to inhibit adenylate cyclase.
B C, Rabin, T Z, Guo, M, Maze
openaire +2 more sources

Efficacy and adverse effects of three delivery methods for aerosolized salbutamol in anesthetized European moose (Alces alces alces): a case series

Acta Veterinaria Scandinavica
Background Wild and captive European moose (Alces alces alces) are routinely anesthetized with drug combinations including alpha-2 adrenoceptor agonists, dissociative anesthetics, and opioids.
Jacopo Morelli +5 more
doaj +1 more source

A NEW GUANIDINE DERIVATIVE: DISSOCIATION OF THE ADRENERGIC NEURON BLOCKING ACTIVITY FROM LOCAL ANESTHETIC ACTIVITY

Japanese Journal of Pharmacology, 1976
Effects of 4-7-exo-methylene-hexahydroisoindoline-ethyl-guanidine hemisulfate (No. 865-123), a new guanidine derivative, on adrenergic neurons and its local anesthetic activity were investigated in comparison with guanethidine. Both derivatives produced in a dose-dependent manner a progressive irreversible reduction of positive chronotropic and ...
Y, Misu, H, Nishio, T, Hosotani, S, Hamano +3 more
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Evaluation of dissociative anesthetic-induced neurotoxicity in human iPSC-derived neurons