Results 61 to 70 of about 22,096 (288)

Hearing voices, dissociation and the self: a functional-analytic perspective [PDF]

, 2016
Item does not contain fulltextIn the current paper, we review existing models of the aetiology of voice hearing. We summarise the argument and evidence that voice hearing is primarily a dissociative process, involving critical aspects of self. We propose
Barnes-Holmes, Yvonne, Dillon, Jacqui, Egger, Jos, McEnteggart, Ciara, Oliver, Joseph E   +4 more
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Understanding Dissociative Identity Disorder

, 2023
Dissociative Identity Disorder (DID), formerly referred to as Multiple Personality Disorder, is a multifaceted psychiatric disorder distinguished by the coexistence of two or more discrete identities or personality states inside an individual (Saville-Smith, 2017).
openaire   +2 more sources

Unravelling psychiatric heterogeneity and predicting suicide attempts in women with trauma-related dissociation using artificial intelligence

European Journal of Psychotraumatology, 2022
Background: Suicide is a leading cause of death, and rates of attempted suicide have increased during the COVID-19 pandemic. The under-diagnosed psychiatric phenotype of dissociation is associated with elevated suicidal self-injury; however, it has ...
Suhas Srinivasan, Nathaniel G. Harnett, Liang Zhang, M. Kathryn Dahlgren, Junbong Jang, Senbao Lu, Benjamin C. Nephew, Cori A. Palermo, Xi Pan, Mohamed Y. Eltabakh, Blaise B. Frederick, Staci A. Gruber, Milissa L. Kaufman, Jean King, Kerry J. Ressler, Sherry Winternitz, Dmitry Korkin, Lauren A. M. Lebois   +17 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The risk-taking and self-harm inventory for adolescents: Development and psychometric evaluation [PDF]

, 2010
In this study, we report on the development and psychometric evaluation of the Risk-Taking (RT) and Self-Harm (SH) Inventory for Adolescents (RTSHIA), a self-report measure designed to assess adolescent RT and SH in community and clinical settings.
Fearon, Pasco R. M., Fonagy, Peter, Roussow, Trudie, Vrouva, Ioanna   +3 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Persons Versus Brains: Biological Intelligence in Human Organisms [PDF]

, 2001
I go deep into the biology of the human organism to argue that the psychological features and functions of persons are realized by cellular and molecular parallel distributed processing networks dispersed throughout the whole body.
Steinhart, E.
core  

Psychopathological risk in parentally bereaved adolescents [PDF]

, 2016
For a child, the death of a parent is a traumatic experience and can give rise to several difficulties during the child’s development. International literature in this field has focused on clinical populations; evaluations of the psychological ...
BALLAROTTO, GIULIA, CERNIGLIA, LUCA, CIMINO, SILVIA, ERRIU, MICHELA   +3 more
core   +1 more source