Results 101 to 110 of about 944,725 (293)

Mesoporous Silica Nanoparticle as a Potential Nanocarrier to Improve the Effectiveness of Antiobesity Drugs

open access: yesDiabetes, Metabolic Syndrome and Obesity
Diah Lia Aulifa,1 Siti Nunung Nurulaini,1 Zahra Noor Silmi Hermawan Ayodduki,1 Joseph Fide Anggi,1 Joshua Harry Chandra,2 Arif Budiman2 1Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang,
Aulifa DL   +5 more
doaj  

Formulation and evaluation of new oxycodone extended release multiple unit pellet system

open access: yesEuropean Pharmaceutical Journal, 2019
The goal of the present study is to prepare a stable, multiple-unit, extended-release dosage form containing oxycodone pellets coated with aqueous ethylcellulose (EC) dispersion, Surelease E-7-19050.
Husár Š.   +4 more
doaj   +1 more source

Synthesis and Dissolution of Metal Oxides in Ionic Liquids and Deep Eutectic Solvents

open access: yesMolecules, 2019
Ionic liquids (ILs) and deep eutectic solvents (DESs) have proven to be suitable solvents and reactants for low-temperature reactions. To date, several attempts were made to apply this promising class of materials to metal oxide chemistry, which ...
Janine Richter, Michael Ruck
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

PROSPECTS OF APPLYING HEAT PUMPS UPON CARRYING OUT COMBINED MASS TRANSFER PROCESSES

open access: yesТонкие химические технологии, 2018
The prospects of using heat pumps for the separation of mixtures by combination of different mass transfer processes are considered, which is associated with the supply and removal of thermal energy.
G. A. Nosov, M. V. Mikhailov
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

The Properties of Treating Waste Printed Circuit Boards by Ionic Liquids

open access: yesJournal of Harbin University of Science and Technology, 2019
Improper treatment about waste printed circuit boards (WPCBs) can cause serious environmental pollution and resources waste. In this study, 1-butyl3-methyl-imidazolium hydrogen sulfate ([Bmim]HSO4) was synthesized through two-step reaction Separation ...
DONG Jing-hao   +4 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Effects of Leaching Parameters on the Impurity Ion Concentrations at Ulexite Ore Leaching: An Experimental Design Approach [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2019
An experimental study was conducted to determine the effects of the leaching parameters on impurity ion concentrations of the liquid phase in ulexite leaching. Powdered ulexite ore was leached in an aqueous medium with sulfur dioxide.
Vedat Kucuk, Mehmet Muhtar Kocakerim
doaj  

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