Results 111 to 120 of about 1,178,957 (338)
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
A Relation between the Radial Velocities of Spiral Nebulæ and the Velocity of Dissolution of Matter [PDF]
Arthur Haas
openalex +1 more source
Does cohabitation prior to marriage raise the risk of marital dissolution and does this effect vary geographically? [PDF]
A number of studies show that premarital cohabitation increases the risk of subsequent marital dissolution. Some argue that this is a consequence of selection effects and that once these are controlled for premarital cohabitation has no effect on ...
Hill Kulu, Paul J. Boyle
core
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo+5 more
wiley +1 more source
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers+3 more
wiley +1 more source
Sur les piles a électrodes identiques, et sur les valeurs des pressions de dissolution [PDF]
B. Brunhes, J. C. Guyot
openalex +1 more source
Influence of chemical reaction kinetics on electrokinetic remediation modelling results [PDF]
A numerical model describing transport of multiple species and chemical reactions during electrokinetic treatment is presented. The transport mechanisms included in the model were electromigration and electroosmosis.
Ceccarini, Alessio+5 more
core
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo+8 more
wiley +1 more source
The Genetics of Partnership Dissolution
There is a genetic component to divorce risk, but little is known about which, and how genetically influenced traits are involved. Using genetic data from the Norwegian Mother, Father, and Child Cohort Study (MoBa), paired with population registers, we perform the first genome-wide association study of partnership dissolution (N=121408).
Ruth Eva Jørgensen+3 more
openaire +2 more sources
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source