Results 31 to 40 of about 371,966 (313)

Supramolecular Strategy Effects on Chitosan Bead Stability in Acidic Media: A Comparative Study

open access: yesGels, 2019
Chitosan beads attract interest in diverse applications, including drug delivery, biocatalysis and water treatment. They can be formed through several supramolecular pathways, ranging from phase inversion in alkaline solutions, to the ionic crosslinking ...
Andrew J. Worthen   +2 more
doaj   +1 more source

Gallstone Dissolution

open access: yesSurgical Clinics of North America, 1990
Many methods are available for gallstone dissolution, including oral bile salts; cholesterol solvents such as mono-octanoin or methyl tert-butyl either; and calcium or pigment solvents such as EDTA and polysorbate. Which of these approaches will be appropriate for an individual patient depends on the type of stones; whether they are in the gallbladder ...
M A, Talamini, T R, Gadacz
openaire   +2 more sources

Uv Spectrophotometric Method For Determination Of The Dissolution Profile Of Rivaroxaban

open access: yes, 2014
Rivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV spectrophotometric method was developed for the determination of rivaroxaban content in pharmaceutical formulations and the ...
Celebier, Mustafa   +3 more
core   +1 more source

Heat affected zone in surfacing chromium ledeburitic steel [PDF]

open access: yesMetalurgija, 2010
Tools get failured during work; wear is a major factor that contributes to failures. Damaged tools are replaced or filed. This paper describes typical changes that occur in the heat affected zone of tool (HAZ), which was repaired by surfacing with a TIG ...
M. Tonkovič Prijanovič, L. Kosec
doaj  

Comparative Application of PLS and PCR Methods to Simultaneous Quantitative Estimation and Simultaneous Dissolution Test of Zidovudine - Lamivudine Tablets

open access: yesActa Chimica Slovenica, 2015
In the development strategies of new drug products and generic drug products, the simultaneous in-vitro dissolution behavior of oral dosage formulations is the most important indication for the quantitative estimation of efficiency and biopharmaceutical ...
Özgür Üstündağ   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Development and characterization of nanosuspensions of olmesartan medoxomil for bioavailability enhancement

open access: yesJournal of Pharmacy and Bioallied Sciences, 2011
Background : Olmesartan medoxomil (OLM), an anti-hypertensive agent administered orally has absolute bioavailability of only 26% due to the poor aqueous solubility (
Hetal Paresh Thakkar   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Dissolution Stability Study of Cefadroxil Extemporaneous Suspensions [PDF]

open access: yes, 2008
Dissolution studies have become matter of great significance because, in most cases, drug dissolution is the rate-limiting step in the absorption process.
Noelia L. Gonzalez Vidal   +8 more
core   +1 more source

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