Results 41 to 50 of about 446,173 (311)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Indonesian Journal of Chemistry, 2020 In drug release kinetics, the drug-matrix interaction is one of the important mechanisms to be dictated. Unfortunately, there is still minimum information discussing the effect of interaction between a drug and its matrix to the release profile of the ...
Muhammad Al Rizqi Dharma Fauzi +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The impact of water flow rate on the dynamic dissolution kinetics of fractured limestone formations
Frontiers in Earth ScienceTo break through the lithological constraints on the surrounding rock for the construction of underground water-sealed oil storage caverns, and considering limestone as a potential host rock for such caverns, the dynamic evolution law of fracture ...
Dabao Xu +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Investigation of variability of primary materials on the intrinsic dissolution behavior of carbamazepine [PDF]
, 2008 Carbamazepine (CBZ) is a poorly water soluble drug, classified as class II according to the Biopharmaceutics Classification System and exhibits at least four polymorphic forms and a dihydrate.
Sehic, Selma
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Kuangchan zonghe liyongArsenopyrite is a common gold-bearing mineral, and the presence of arsenic leads to difficulties in gold recovery. In this paper, the effects of leaching time, NaOH concentration, temperature and potassium permanganate concentration on the arsenic ...
Kai JIN +4 more
doaj +1 more source
Dissolution of Cavities and Porous Media: a Multi-Scale View [PDF]
, 2013 Dissolution of underground cavities or porous media involves many different scales that must be taken into account in modeling attempts. This paper presents a review of some of these problems.
Quintard, Michel
core