Results 61 to 70 of about 215,287 (265)
Effect of glycerin on indomethacin release profile from their liquisolid compacts
Journal of Mazandaran University of Medical Sciences, 2009 (Received 28 Sep, 2008 ; Accepted 6 May, 2009)AbstractBackground and purpose: The increasing effect of liquisolid systems on dissolution behavior of poor soluble drugs has been proved.
Majid Saeedi +3 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2021 Belachew Umeta,1 Anbessa Bekele,1 Tesfaye Mohammed,1,2 Markos Duguma,2 Henok Teshome,2 Yimer Mekonnen1,2 1Department of Pharmaceutical Sciences, School of Pharmacy, Institute of Health, Jimma University, Jimma, Oromia, Ethiopia; 2Jimma University ...
Umeta B +5 more
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Frontiers in Chemistry, 2019 Shape-controlled precious metal nanoparticles have attracted significant research interest in the recent past due to their fundamental and scientific importance.
Ruttala Devivaraprasad +3 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Solubility investigation of ketone and phenol essential oils in water using spectrometry and GC/MS [PDF]
Research Journal of Pharmacognosy, 2017 Background and objectives: Essential oils are used for their flavors and fragrances and their medicinal properties in food, cosmetic, agriculture and pharmaceutical industries.
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Chalcopyrite Dissolution at 650 mV and 750 mV in the Presence of Pyrite
Metals, 2015 The dissolution of chalcopyrite in association with pyrite in mine waste results in the severe environmental issue of acid and metalliferous drainage (AMD).
Yubiao Li +3 more
doaj +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Tafonomia de Foraminíferos Bentônicos em Sedimentos Siliciclásticos e Carbonáticos [PDF]
Anuário do Instituto de Geociências, 2007 Biological, physical and chemical features work on the bioclasts, which react specifically under diverse environmental conditions. As consequence of the environment stress, the taphonomic signature onforaminiferal tests provides significant ...
Mariana Nunes Cardoso +1 more
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