Results 71 to 80 of about 494,411 (264)
Разработка и регистрация лекарственных средств, 2020 Introduction. 1-[2-(2-benzoylphenoxy)ethyl]-6-methyluracil is a substance of scientific interest intended for the treatment of HIV-infection. However, its low bioavailability is a major limitation in successful drug delivery by oral route. Therefore, the
D. V. Demchenko +4 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
, 2011 The Biopharmaceutics Classification System (BCS) is a tool that was created to categorize drugs into different groups according to their solubility and permeability characteristics.
ISSA, Michele G., FERRAZ, Humberto G.
core
The anodic dissolution of covellite in acidic, chloride solutions [PDF]
, 2010 An electrochemical study was conducted on a stationary, synthetically produced, covellite electrode in acidic, chloride solutions at ambient conditions to investigate the dissolution behaviour of the mineral over a surface potential range from the open ...
Basson, Petrus
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Investigation of variability of primary materials on the intrinsic dissolution behavior of carbamazepine [PDF]
, 2008 Carbamazepine (CBZ) is a poorly water soluble drug, classified as class II according to the Biopharmaceutics Classification System and exhibits at least four polymorphic forms and a dihydrate.
Sehic, Selma
core +1 more source
Effect of glycerin on indomethacin release profile from their liquisolid compacts
Journal of Mazandaran University of Medical Sciences, 2009 (Received 28 Sep, 2008 ; Accepted 6 May, 2009)AbstractBackground and purpose: The increasing effect of liquisolid systems on dissolution behavior of poor soluble drugs has been proved.
Majid Saeedi +3 more
doaj
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
A review of the antecedents of union dissolution [PDF]
The question of what factors contribute to the stability of coresidential partnerships has attracted the attention of many social scientists. This study summarizes recent research on the determinants of union dissolution within a set of substantive ...
Torkild Lyngstad, Marika Jalovaara
core
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source