Results 101 to 110 of about 2,889,262 (312)
Chemical improvement of soluble rocks: Foundation of Mosul Dam as case study
Scientific ReportsThe dissolution of soluble rocks (gypsum/anhydrite) beneath the Mosul Dam by water seepage has been observed upon the initial impoundment; consequently, several sinkholes have been manifested in the vicinity of the dam site. Traditional grouting has been
Aram Aziz +4 more
doaj +1 more source
Improvement in vitro Dissolution Rate of Quercetin Using Cocrystallization of Quercetin-Malonic Acid
Indonesian Journal of Chemistry, 2018 The aim of the study was to improve the in-vitro dissolution rate of quercetin (Qu) using cocrystallization of quercetin. Cocrystals of quercetin (Co Qu) were produced with malonic acid (Ma) as coformer at ratio 1:2 using solvent evaporation method ...
Dwi Setyawan +3 more
doaj +1 more source
In situ controlled crystallization as a tool to improve the dissolution of Glibenclamide
International Journal of Pharmaceutics, 2012 For pharmaceutical purpose, micro-sized drugs are needed for many delivery systems, such as pulmonary and oral drug delivery systems. Many strategies have been employed to reduce the particle size of poorly water soluble drugs. Microcrystals could be produced by controlled association of drug in order to obtain naturally grown particles.
Elkordy, Amal, Jatto, A, Essa, E A
openaire +3 more sources
A review of the antecedents of union dissolution [PDF]
The question of what factors contribute to the stability of coresidential partnerships has attracted the attention of many social scientists. This study summarizes recent research on the determinants of union dissolution within a set of substantive ...
Torkild Lyngstad, Marika Jalovaara
core
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Production of Co-Siderophore Complexes by Ligand-Promoted Dissolution
, 2009 Recent research indicates that siderophores, a class of biogenic ligands with known exceptional affinity for Fe(III), can also strongly complex Co(III), an element essential to normal metabolic function of microbes and animals.
Bi, Yuqiang
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The dissolution of gold colloids in aqueous thiosulfate solutions [PDF]
, 2008 The kinetics of the dissolution of gold and silver colloids in ammoniacal thiosulfate solutions has been studied using oxygen, copper(II) or oxygenated copper(II) as oxidants at pH 9 - 11 and temperature 22oC to 48oC.
Zhang, Xinmin
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Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Improvement in Dissolution of Liver Fibrosis in an Animal Model by Tetrathiomolybdate
Experimental Biology and Medicine, 2009 The background for this study is that we have observed some improvement in cirrhosis in Wilson’s disease patients treated with the anticopper medicine, zinc, and another anticopper drug, tetrathiomolybdate, has completely prevented hepatic fibrosis in the carbon tetrachloride mouse model.
Guoqing, Hou +2 more
openaire +2 more sources