Results 91 to 100 of about 2,889,262 (312)
Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of musculo-skeletal and joint disorders. The problem with this drug is its poor solubility in water and hence poor bioavailability after oral administration.
Eman B. H. Al-Khedairy
doaj +3 more sources
Lithium bis(fluorosulfonyl)imide has emerged as a promising alternative to lithium hexafluorophosphate as conducting salt in battery electrolytes due to its favorable physicochemical properties.
Peng Yan +7 more
doaj +1 more source
In order to improve the specific capacity and rate capability of the electrodeposited Sn-Ni alloy, a post electrochemical dissolution treatment was introduced to prepare porous Sn-Ni alloy.
Chunhui Tan +7 more
doaj +1 more source
Dissolution improvement of binary solid dispersions of erlotinib prepared by one-step electrospray method. [PDF]
Jahangiri A, Khalilzad F, Barghi L.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Improvement of the Dissolution Rate of Silymarin by Means of Solid Dispersions
Solid dispersions of silymarin were prepared by the fusion method with the intention of improving the dissolution properties of silymarin. Polyethylene glycol 6000 (PEG 6000) was used as the inert hydrophilic matrix. The dissolution studies of the solid dispersions were performed in vitro.
Li, Feng-Qian, Hu, Jin-Hong
openaire +3 more sources
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
This report shares learning from the collaborative, including which factors contributed to high levels of appropriate prophylaxis and to improvement. There was a higher level of appropriateness observed in orthopaedic and post-partum patients than in ...
National Medication Safety Improvement Programme
core
Triboelectrification and dissolution property enhancements of solid dispersions [PDF]
The use of solid dispersion techniques to modify physicochemical properties and improve solubility and dissolution rate may result in alteration to electrostatic properties of particles.
Conway, Barbara R +12 more
core +1 more source
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source

