Results 301 to 310 of about 5,089,703 (351)

Improving Dissolution of Meloxicam Using Solid Dispersions

2006
Meloxicam is a poorly water soluble non steroidal anti-inflammatory drug and antipyretic agent. The aim of the present work was to investigate the effect of different types of carriers on in vitro dissolution of meloxicam. Meloxicam solid dispersions were prepared by physical mixing, co-grinding and solvent evaporation methods with polyethylene glycol (
Dehghan, MH, Jafar, M
openaire   +1 more source

Ibuprofen–phospholipid solid dispersions: Improved dissolution and gastric tolerance

International Journal of Pharmaceutics, 2012
Solid dispersions of ibuprofen with various phospholipids were prepared, and the effect of phospholipids on the in vitro dissolution and in vivo gastrointestinal toxicity of ibuprofen was evaluated. Most phospholipids improved the dissolution of ibuprofen; dimyristoylphosphatidyl-glycerol (DMPG) had the greatest effect.
M Delwar, Hussain, Vipin, Saxena, James F, Brausch, Rahmat M, Talukder   +3 more
openaire   +2 more sources

An investigation into solubility and dissolution improvement of alectinib hydrochloride as a third-generation amorphous solid dispersion

Journal of Drug Delivery Science and Technology, 2023
S. Saha, A. Joshi, Romi Singh, Suvamay Jana, K. Dubey   +4 more
semanticscholar   +1 more source

Naftopidil Molecular Salts with Improved Dissolution and Permeation

Crystal Growth & Design, 2020
Naftopidil (NFPD) is a α1 adrenoceptor antagonist drug. Low solubility and low permeability are the major drawbacks of this drug.
M. K. Chaitanya Mannava, Rambabu Dandela, Srinu Tothadi, K. Anand Solomon, Ashwini K. Nangia   +4 more
openaire   +1 more source

Intercalation of olanzapine into CaAl and NiAl Layered Double Hydroxides for dissolution rate improvement: Synthesis, characterization and in vitro toxicity

Journal of Drug Delivery Science and Technology, 2019
The aim of this work was to develop and characterize different Layered Double Hydroxides (LDHs) loaded with of Olanzapine (OLZ), CaAl:OLZ and NiAl:OLZ, by thermogravimetry (TG), differential scanning calorimetry (DSC), Fourier Transform Infrared ...
J. G. Pontes‐Neto, M. A. M. Lyra, M. Soares, L. L. Chaves, J. L. Soares‐Sobrinho   +4 more
semanticscholar   +1 more source

Improvement of nifedipine dissolution characteristics using supercritical CO2

International Journal of Pharmaceutics, 1997
Abstract An application of supercritical fluids (SCFs) for processing of pharmaceuticals is presented. PGSS (Particles from Gas Saturated Solutions), a novel method for high pressure material processing, has been used to improve technological characteristics of the poorly water soluble calcium antagonist nifedipine.
Petra Senčar-Božič, Stane Srčič, Zeljko Knez, Janez Kerč   +3 more
openaire   +1 more source

Rapamycin-cyclodextrin complexation: improved solubility and dissolution rate

Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2010
The objective of this study was to improve poor aqueous solubility and dissolution properties of anticancer drug rapamycin through formation of inclusion complexes with natural and modified cyclodextrins. Of the cyclodextrins tested, γ-cyclodextrin and hydroxypropyl-γ-cyclodextrin did not complex with rapamycin.
M. Abdur Rouf, Imran Vural, Erem Bilensoy, Atilla Hincal, Dilek Demir Erol   +4 more
openaire   +1 more source

Pharmaceutical cocrystals of naringenin with improved dissolution performance

CrystEngComm, 2018
Four pharmaceutical cocrystals of naringenin were obtained, which demonstrate improved dissolution performance.
Chun Luo, Wendong Liang, Xin Chen, Jianming Wang, Zongwu Deng, Hailu Zhang   +5 more
openaire   +1 more source

An Improved Method for Dissolution of Uranium Tetrafluoride.

Analytical Chemistry, 1962
Dissolution of UF/sub 4 in a mixture of (NH/sub 4/)/sub 2/ SO/sub 4/ and H/s ub 2/SO/sub 4/ and boric acid is described. For large-sized samples, addition of boric acid appreciably hastened dissolution, and a 15-gram sample was dissolved in 30 min in quartz glassware. The cooled melt is soluble in distilled water. (M.C.G.)
W. M. Wise, H. R. Soehnlin, C. H. McBride   +2 more
openaire   +1 more source

Saturation Solubility and Dissolution Property Improvement of Albendazole by Salt Formation Approach

Journal of Pharmaceutical Innovation, 2021
Mohini Patel, Dhaval D. Mori, Kiran Dudhat, Sunny Shah, J. Chavda, Ajay I. Patel   +5 more
semanticscholar   +1 more source