Results 81 to 90 of about 555,478 (356)

Evolution of anodic stress corrosion cracking in a coated material [PDF]

, 2010
In the present paper, we investigate the influence of corrosion driving forces and interfacial toughness for a coated material subjected to mechanical loading. If the protective coating is cracked, the substrate material may become exposed to a corrosive
Bjerkén, C., Ortiz, M.
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Solid Dispersions of Genistein via Solvent Rotary Evaporation for Improving Solubility, Bioavailability, and Amelioration Effect in HFD-Induced Obesity Mice

Pharmaceutics
Genistein (GEN) is an active pharmaceutical ingredient that presents the challenges of poor water solubility and low oral bioavailability.
Chenxu Qiu, Yancui Zhang, Yingsai Fan, Shupeng Li, Jianting Gao, Xin He, Xinghua Zhao   +6 more
doaj   +1 more source

Reservoir theory for studying the geochemical evolution of soils [PDF]

, 2010
[1] Linking mineral weathering rates measured in the laboratory to those measured at the landscape scale is problematic. In laboratory studies, collections of minerals are exposed to the same weathering environment over a fixed amount of time. In natural
Almond, Amundson, Anderson, Anderson, Anderson, Baldwin, Birkeland, Blum, Brantley, Brantley, Brown, Burke, Butler, Carson, Chadwick, Dietrich, Dietrich, Dixon, Eriksson, Fernandes, Ferrier, Furbish, Gabet, Gabet, Gabet, Heimsath, Heimsath, Hren, Jenny, Johnson, Johnson, Kaste, Kirkby, Kyungsoo Yoo, Lebedeva, Montgomery, Mudd, Mudd, Mudd, Nikiforoff, Porder, Porder, Prosser, Riebe, Riebe, Rodhe, Roering, Roering, Simon Marius Mudd, Small, Trumbore, Waldbauer, Walker, West, White, Yoo, Yoo, Yoo, Yoo   +58 more
core   +2 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

A revised scheme for the reactivity of iron (oxyhydr)oxide minerals towards dissolved sulfide [PDF]

, 2004
The reaction between dissolved sulfide and synthetic iron (oxyhydr)oxide minerals was studied in artificial seawater and 0.1 M NaCl at pH 7.5 and 25°C. Electron transfer between surface-complexed sulfide and solid phase Fe(III) results in the oxidation ...
Bartlett, Berner, Biber, Bigham, Bondietti, Borggaard, Canfield, Canfield, Canfield, Canfield, Canfield, Carlson, Chambers, Chen, Cline, Cornell, Cornell, Crosby, Davis, Dos Santos Afonso, Fitzpatrick, Fredrickson, Fuller, Gagnon, Haese, Hering, Heron, Hurtgen, Jørgensen, Kostka, Krom, Krom, LaKind, Litter, Lovley, Lovley, Luther III, Luther III, Michael D. Krom, Millero, Morse, Morse, Morse, O’Brien, Peiffer, Postma, Poulton, Poulton, Poulton, Poulton, Pyzik, Raiswell, Raiswell, Rickard, Robert Raiswell, Roden, Rysgaard, Schwertmann, Schwertmann, Schwertmann, Schwertmann, Sidhu, Simon W. Poulton, Stolz, Stookey, Stucki, Stumm, Suter, Taylor, Thamdrup, Thamdrup, Torrent, Urban, Viollier, West, Yao, Zhang, Zinder   +77 more
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Investigation of the in vitro performance difference of drug-Soluplus® and drug-PEG 6000 dispersions when prepared using spray drying or lyophilization

Saudi Pharmaceutical Journal, 2017
Purpose: To evaluate the physicochemical and in vitro characteristics of solid dispersions using BCS II model drugs with Soluplus® and one of its component homopolymers, PEG 6000.
Mohammad A. Altamimi, Steven H. Neau
doaj   +1 more source

Mixing across fluid interfaces compressed by convective flow in porous media

, 2017
We study the mixing in the presence of convective flow in a porous medium. Convection is characterized by the formation of vortices and stagnation points, where the fluid interface is stretched and compressed enhancing mixing.
Dentz, Marco, Hidalgo, Juan J.
core   +1 more source