Study on Dissolution Thermodynamics and Cooling Crystallization of Rifamycin S [PDF]
ACS Omega, 2021 The solubility data of rifamycin S were measured in isopropanol, butyl acetate, and their mixed solvents across the temperature range of 283.15-323.15 K by the gravimetric method. The results demonstrate that the solubility of rifamycin S increases with the increasing temperature in the two pure solvents, and in the mixed solvents, it increases first ...
Kui Chen +5 more
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Chiral Recognition R- and RS- of New Antifungal: Complexation/Solubilization/Dissolution Thermodynamics and Permeability Assay [PDF]
Pharmaceutics, 2022 Novel potential antifungal of 1,2,4-triazole class have been synthesized as pure enantiomer (R-98) and racemic (RS-186). The effect of 2-hydroxypropyl-β-cyclodextrin (CD) on the solubility and permeability of RS-186 and R-98 in terms of chiral ...
Tatyana V. Volkova +3 more
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Dissolution Thermodynamics of the Solubility of Sulfamethazine in (Acetonitrile + 1-Propanol) Mixtures [PDF]
PharmaceuticalsBackground: Solubility is one of the most important parameters in the research and development processes of the pharmaceutical industry. In this context, cosolubility is one of the most used strategies to improve the solubility of poorly soluble drugs ...
Daniel Ricardo Delgado +4 more
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Hot-melt extruded ibuprofen ternary solid dispersions using in-line UV–Vis: Impact of an ionizable polymer on thermodynamics and dissolution [PDF]
International Journal of Pharmaceutics: XAmorphous solid dispersions (ASDs) remain a key strategy for enhancing the dissolution of poorly soluble APIs. Building on previous work with binary ibuprofen (IBU) blends, this study investigates the impact of incorporating poly(butyl methacrylate-co-(2-
Matheus de Castro +9 more
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LiquidsPublished equilibrium mole fraction solubilities of phenothiazine in ethanol, propylene glycol and water as mono-solvents at several temperatures were investigated to find standard apparent thermodynamic quantities of dissolution mixing and solvation ...
Fleming Martínez +2 more
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Thermodynamic Study of Deferiprone Dissolution in Polyethylene Glycol 400 and 2-Propanol Mixture [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2023 In the current study, the solubility and density of deferiprone were determined in the polyethylene glycol (PEG) 400 and 2-propanol mixtures at 293.2 – 313.2 K using a shake-flask method before a spectrophotometric method.
Mahsa Ahmadi +4 more
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Solubility, Correlation, Dissolution Thermodynamics and Preferential Solvation of Meloxicam in Aqueous Mixtures of 2-Propanol [PDF]
Pharmaceutical Sciences, 2022 Background: Meloxicam is a powerful analgesic and anti-inflammatory drug widely prescribed by physicians in current therapeutics. Because of the very low aqueous equilibrium solubility of meloxicam, this property has been studied in {2-propanol + water ...
Darío A Tinjacá +4 more
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Solubility and Thermodynamic Data of Febuxostat in Various Mono Solvents at Different Temperatures
Molecules, 2022 This study examines the solubility and thermodynamics of febuxostat (FBX) in a variety of mono solvents, including “water, methanol (MeOH), ethanol (EtOH), isopropanol (IPA), 1-butanol (1-BuOH), 2-butanol (2-BuOH), ethylene glycol (EG), propylene glycol (
Nazrul Haq +3 more
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Significant Increase in the Solubility of Celecoxib in Presence of Some Deep Eutectic Solvents as Novel Sustainable Solvents and the Thermodynamic Analysis of These Systems [PDF]
Pharmaceutical Sciences, 2020 Background: Deep eutectic solvents (DESs) exist a wide variety of potential and existing applications. Based on the fact that the choline chloride (ChCl) is a complex B vitamin and widely used as food additive, the choline-based DESs are generically ...
Hemayat Shekaari +5 more
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Crystallization Thermodynamics of α-Lactose Monohydrate in Different Solvents
Pharmaceutics, 2022 It is common to find that some of the lactose in dairy powders and pharmaceutical tablets is present in the unstable amorphous state. Therefore, their crystallization thermodynamics in different solvents are particularly important.
Youliang Guan +3 more
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