Results 51 to 60 of about 1,243,090 (307)

Pediatric distal metaphysis fractures of the humerus: etiopathogenesis, clinical features, diagnostics, treatment

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Backgrоund. Distal metaphysis fractures of the humerus in children are the most common among elbow joint injuries in children, occurring in 64–70%. Aim.
O. N. Amairi, I. F. Akhtyamov, I. V. Tsoy, P. S. Andreev   +3 more
doaj   +1 more source

Radical Resection of a Recurrent Giant Cell Tumor of the Distal Ulna and Immediate Reconstruction With a Distal Radio-Ulnar Joint Implant Arthroplasty

, 2020
Background: Giant cell tumors (GCTs) of the distal ulna are rare. Despite being benign, they can be locally aggressive and may recur following conventional treatment by curettage and bone grafting. Salvage reconstructive options after failed conventional
Graham, DJ, Jones, NF
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Molecular Pathways and Key Genes Associated With Breast Width and Protein Content in White Striping and Wooden Breast Chicken Pectoral Muscle

Frontiers in Physiology, 2022
Growth-related abnormalities affecting modern chickens, known as White Striping (WS) and Wooden Breast (WB), have been deeply investigated in the last decade. Nevertheless, their precise etiology remains unclear.
Martina Bordini, Francesca Soglia, Roberta Davoli, Martina Zappaterra, Massimiliano Petracci, Adele Meluzzi   +5 more
doaj   +1 more source

An autopsy study of a familial oculopharyngeal muscular dystrophy (OPMD) with distal spread and neurogenic involvement [PDF]

, 1981
An 81-year-old man from a family with a history of oculopharyngeal muscular dystrophy (OPMD) involving 6 members over 4 generations is described. The patient first noted drooping of his eyelids at the age of 65.
Krause, Klaus-Henning, Schmitt, H.-P.
core   +1 more source

Flexor Carpi Radialis Tendon Rupture in a Distal Radius Malunion

, 2022
We describe a rare case of complete rupture of the flexor carpi radialis in a distal radius malunion. Though the tendon was not repaired, the functional result was acceptable.
Seo, Lauren, Lauren Seo, Ronit Wollstein, Wollstein, Ronit   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Red light and biostimulants containing arbuscular mycorrhizal fungi enhance ajmalicine and serpentine production in Catharanthus roseus under indoor conditions

Scientific Reports
Indoor farming offers optimal conditions for high and stable ajmalicine and serpentine yields in Catharanthus roseus, enabling precise control over environmental stimuli such as light and biostimulants.
Alessandro Quadri, Bianca Sambuco, Mattia Trenta, Patrizia Tassinari, Daniele Torreggiani, Laura Mercolini, Michele Protti, Alessandra Zambonelli, Federico Puliga, Alberto Barbaresi   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The ground beetle Pseudoophonus rufipes gut microbiome is influenced by the farm management system

Scientific Reports, 2022
Intensive conventional farm management, characterized by high agrochemicals input, could alter the composition of microbial communities with potential negative effects on both functional traits and the ecosystem services provided.
Serena Magagnoli, Daniele Alberoni, Loredana Baffoni, Antonio Martini, Francesca Marini, Diana Di Gioia, Martina Mazzon, Claudio Marzadori, Gabriele Campanelli, Giovanni Burgio   +9 more
doaj   +1 more source