Results 161 to 170 of about 10,229,767 (397)
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park+8 more
wiley +1 more source
Determination of the Elements of the Orbit of a Planet or a Comet by means of the Variation of Two Geocentric Distances [PDF]
M. T. Subbotin, A. C. D. Crommelin
openalex +1 more source
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu+3 more
wiley +1 more source
ISOLATION BY DISTANCE UNDER DIVERSE SYSTEMS OF MATING [PDF]
Sewall Wright
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Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam+2 more
wiley +1 more source
On Tests of Normality and Other Tests of Goodness of Fit Based on Distance Methods [PDF]
Mark Kac, J. Kiefer, J. Wolfowitz
openalex +1 more source
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang+8 more
wiley +1 more source
On a certain distance of sets and the corresponding distance of functions [PDF]
Edward Marczewski, Hugo Steinhaus
openalex +1 more source
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
La evaluación de las intenciones y competencias emprendedoras de los estudiantes de modalidad a distancia no se ha tenido demasiado en cuenta, por lo que se aplicó el cuestionario GUESSS a 2458 discentes de la Universidad Nacional de Educación a ...
Francisco José Rubio Hernández+2 more
doaj +1 more source