Results 141 to 150 of about 3,907,799 (305)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Course/Materials Development for Distance Education: Additional Readings and Exercises

open access: yes
Note: No date of issue was indicatedThis contains Course/Materials Development for Distance Education sessions on the following topics: (1.) Part 1 - Planning materials development: where do we begin, Part 2 -The target audience: profiling your learners,
The Distance Education Center of The University of the West Indies and The International Extension College
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Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Accessible Elements: Teaching Science Online and at a Distance [PDF]

open access: yes, 2010
Accessible Elements informs science educators about current practices in online and distance education: distance-delivered methods for laboratory coursework, the requisite administrative and institutional aspects of online and distance teaching, and the ...
Dietmar Kennepohl, Lawton Shaw
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Exploring career aspirations and development barriers of university accounting students: the explanatory sequential mixed methods perspectives

open access: yesDiscover Education
Career aspirations and career development are major concerns in national building. This study explored the career aspirations of final year B.Ed. Accounting students in a Ghanaian university and the barriers that prevented them from achieving their ...
Lydia Aframea Dankyi   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Deep Learning and Cognitive Presence in Collaborative Web-Based Learning Environments: Student and Instructor Perspectives

open access: yes, 2006
This study examines the ability of online distance education courses using CMC and constructivist assessment tools to support cognitive presence and deep learning.
Olszewski, L. J. J..
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Looking to the future ... Distance Education Issues in Nebraska [PDF]

open access: yes, 2000
The Nebraska Network 21 (NN21) Action Team on Distance Education/Outreach has studied a variety of issues related to distance education in order to better serve the people of Nebraska.
Action Team, NN21 Distance Education/Outreach
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