Results 51 to 60 of about 8,450,223 (267)
Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy +5 more
wiley +1 more source
We use non-symmetric distances to give a self-contained account of C*-algebra filters and their corresponding compact projections, simultaneously simplifying and extending their general ...
Bice, Tristan, Vignati, Alessandro
core +2 more sources
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane +11 more
wiley +1 more source
Gower and Krzanowski (1999) described the analysis of a multivariate dataset that violated the assumptions of normality for multivariate analysis of variance. They developed a method comprising two aspects: a graphical representation of the points in a fewer number of dimensions, known as principal coordinate analysis; and a technique similar to ...
openaire +2 more sources
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Conditional Distance Correlation [PDF]
Statistical inference on conditional dependence is essential in many fields including genetic association studies and graphical models. The classic measures focus on linear conditional correlations and are incapable of characterizing nonlinear conditional relationship including nonmonotonic relationship.
Xueqin, Wang +4 more
openaire +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Getting the Mix Right Again: An Updated and Theoretical Rationale for Interaction
No topic raises more contentious debate among educators than the role of interaction as a crucial component of the education process. This debate is fueled by surface problems of definition and vested interests of professional educators, but is more ...
Terry Anderson, Canada Research Chair in Distance Education
doaj
An immersive virtual reality communication skills training for dietitians: A feasibility study
Objective: The training of dietitians emphasizes the development of strong communication skills. Immersive virtual reality (IVR) has been successfully employed for various healthcare scenarios; however, it is yet understudied in dietetics education ...
Ivan Moser +2 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

