Results 141 to 150 of about 13,248,588 (381)
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
A Scale Elasticity Measure for Directional Distance Function and its Dual [PDF]
In this paper we introduce a scale elasticity measure based on directional distance function for multi-output-multi-input technologies and explore its fundamental properties.
Valentin Zelenyuk
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Journal of New Theory, 2020 Clustering plays an important role in data mining, pattern recognition and machine learning. This paper proposes Pythagorean neutrosophic clustering methods based on similarity measures between Pythagorean neutrosophic sets with T and F are dependent ...
Mohana Krıshnaswamy, Jansi Rajan
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Medical Diagnosis Using Distance-Based Similarity Measures of Single Valued Neutrosophic Multisets [PDF]
Neutrosophic Sets and Systems, 2015 This paper proposes a generalized distance measure and its similarity measures between single valued neutrosophic multisets (SVNMs). Then, the similarity measures are applied to a medical diagnosis problem with incomplete, indeterminate and inconsistent ...
Shan Ye, Jing Fu, Jun Ye
doaj
The Chord‐Normalized Expected Species Shared (CNESS)‐distance represents a superior measure of species turnover patterns [PDF]
, 2019 Yi Zou, Jan C. Axmacher
openalex +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source