Results 71 to 80 of about 12,223,733 (321)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Calibrated estimators of totals under different distance measures
Lietuvos Matematikos Rinkinys, 2004 There is not abstract.
Aleksandras Plikusas, Dalius Pumputis
doaj +3 more sources
First and second moments for self-similar couplings and Wasserstein distances
, 2014 We study aspects of the Wasserstein distance in the context of self-similar measures. Computing this distance between two measures involves minimising certain moment integrals over the space of \emph{couplings}, which are measures on the product space ...
Fraser, Jonathan M.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Distance Measures for Reduced Ordering Based Vector Filters [PDF]
, 2010 Reduced ordering based vector filters have proved successful in removing long-tailed noise from color images while preserving edges and fine image details.
Astola +29 more
core +1 more source
Belief Interval-Based Distance Measures in the Theory of Belief Functions
IEEE Transactions on Systems, Man, and Cybernetics: Systems, 2018 In belief functions related fields, the distance measure is an important concept, which represents the degree of dissimilarity between bodies of evidence. Various distance measures of evidence have been proposed and widely used in diverse belief function
Deqiang Han, J. Dezert, Yi Yang
semanticscholar +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Distance and Similarity Measures for Soft Sets
, 2010 In [P. Majumdar, S. K. Samanta, Similarity measure of soft sets, New Mathematics and Natural Computation 4(1)(2008) 1-12], the authors use matrix representation based distances of soft sets to introduce matching function and distance based similarity ...
Ali M. I. +5 more
core +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source