Results 101 to 110 of about 13,110,839 (301)

Rejection of Schmidt et al.'s estimators for bear population size

open access: yesEcology and Evolution, 2019
Aerial distance sampling of bears to estimate population size has been used throughout many parts of Alaska. The distance sampling models are complex since they need to account for undetected bears and differences in detection probabilities.
Earl Becker, Aaron Christ
doaj   +1 more source

Short-Distance Cutoffs in Curved Space

open access: yes, 2004
It is shown that space-time may possess the differentiability properties of manifolds as well as the ultraviolet finiteness properties of lattices. Namely, if a field's amplitudes are given on any sufficiently dense set of discrete points this could ...
Kempf, Achim
core   +2 more sources

Community distance sampling models allowing for imperfect detection and temporary emigration

open access: yes, 2017
. Recent developments of community abundance models (CAMs) enable us to analyze communities subject to imperfect detection. However, existing CAMs assume spatial closure, that is, that individuals are always present in the sampling plots, which is often ...
Y. Yamaura, J. Andrew Royle
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Camera trap-based estimates reveal spatial variability in African clawless otter population densities and behaviour

open access: yesOryx
Estimating the population size of shy and elusive species is challenging but necessary to inform appropriate conservation actions for threatened or declining species. Using camera-trap surveys conducted during 2017–2021, we estimated and compared African
Candice B. Lewis   +3 more
doaj   +1 more source

From distance sampling to spatial capture–recapture

open access: yes, 2017
Distance sampling and capture–recapture are the two most widely used wildlife abundance estimation methods. capture–recapture methods have only recently incorporated models for spatial distribution and there is an increasing tendency for distance ...
D. Borchers, T. Marques
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Donor-Acceptor Distance Sampling Enhances the Performance of "Better than Nature" Nicotinamide Coenzyme Biomimetics.

open access: yesJournal of the American Chemical Society, 2016
Understanding the mechanisms of enzymatic hydride transfer with nicotinamide coenzyme biomimetics (NCBs) is critical to enhancing the performance of nicotinamide coenzyme-dependent biocatalysts. Here the temperature dependence of kinetic isotope effects (
A. Geddes   +4 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Accessing camera trap survey feasibility for estimating Blastocerus dichotomus (Cetartiodactyla, Cervidae) demographic parameters

open access: yesIheringia: Série Zoologia, 2017
Demographic information is the basis for evaluating and planning conservation strategies for an endangered species. However, in numerous situations there are methodological or financial limitations to obtain such information for some species.
Pedro Henrique F. Peres   +3 more
doaj   +1 more source

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