Results 51 to 60 of about 1,881,033 (281)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

King Rail (Rallus elegans) response to audio playback: implications for population estimation, monitoring methodology, and trapping approach

open access: yesJournal of Field Ornithology, 2023
Conspecific audio can be broadcast to improve detection probability (detectability) of secretive marsh bird species for population monitoring purposes and as a lure to more effectively trap individuals.
Dustin E. Brewer   +3 more
doaj  

Point and interval estimates of abundance using multiple covariate distance sampling: an example using great bustards. [PDF]

open access: yes, 2009
Previously in the University eprints HAIRST pilot service at http://eprints.st-andrews.ac.uk/archive/00000447/The pdf file contains the tech report, the ASCII (.R) file contains the accompanying R code.Description of computations to produce sex-specific ...
Rexstad, Eric
core  

Flat histogram simulation of lattice polymer systems

open access: yes, 2001
We demonstrate the use of a new algorithm called the Flat Histogram sampling algorithm for the simulation of lattice polymer systems. Thermodynamics properties, such as average energy or entropy and other physical quantities such as end-to-end distance ...
A. Sali   +32 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Investigating distance effects on environmental values: A choice modelling approach [PDF]

open access: yes
This paper describes a Choice Modelling experiment set up to investigate the relationship between distance and willingness to pay for environmental quality changes. The issue is important for the estimation and transfer of benefits.
Giovanni B. Concu
core   +3 more sources

Testing the effects of anthropogenic pressures on a diverse African herbivore community

open access: yesEcosphere, 2020
Large herbivore communities around the world have declined steeply in recent decades. Although excessive bushmeat harvesting is thought to be the primary cause of herbivore declines in many ecosystems, the direct effects of anthropogenic pressures on ...
Milan A. Vinks   +10 more
doaj   +1 more source

Redshift-Distance Survey of Early-type Galaxies. I. Sample Selection, Properties and Completeness

open access: yes, 1999
This is the first in a series of papers describing the recently completed all-sky redshift-distance survey of nearby early-type galaxies (ENEAR) carried out for peculiar velocity analysis.
C. N. A. Willmer   +15 more
core   +1 more source

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