Results 111 to 120 of about 3,101,401 (288)

The nobiliary concept of play as a mechanism for ethical-political distinction in the Late Middle Ages. (El imaginario lúdico de la nobleza como dispositivo de la distinción ético-política en la Baja Edad Media Occidental). [PDF]

open access: yesRevista Internacional de Ciencias del Deporte, 2008
This article examines the problematic meaning, both in concept and practice, of games in the late Middle Ages, using Norbert Elias’ theoretical perspective of the civilizing process.
Manuel Rodríguez López   +1 more
doaj  

In defense of the possibilism–actualism distinction [PDF]

open access: yes, 2020
In Modal Logic as Metaphysics, Timothy Williamson claims that the possibilism-actualism (P-A) distinction is badly muddled. In its place, he introduces a necessitism-contingentism (N-C) distinction that he claims is free of the confusions that ...
Menzel, Christopher
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

KANT’IN TEORİK AKIL-PRATİK AKIL AYRIMINA ELEŞTİREL BİR YAKLAŞIM

open access: yesFelsefe Dünyası, 2020
Kant’ın düşünce sistemi hissetme ile düşünme yetileri arasında yaptığı ayrım üzerinde yükselir. Bu ayrım Kant tarafından temellendirilmemiştir; sistemin bütünü bakımından bir hipotez niteliğindedir.
Aliye Kovanlıkaya
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Yueju – The Formation of a Legitimate Culture in Contemporary Shanghai

open access: yesCulture Unbound: Journal of Current Cultural Research, 2012
This article presents a case study of the development of a local cultural form – Shanghai Yueju – caught up in the rapid urban redevelopment of post-socialist China.
Haili Ma
doaj   +1 more source

Trespass-copyright parallels and the harm-benefit distinction [PDF]

open access: yes, 2009
Responding to Shyamkrishna Balganesh, Foreseeability and Copyright Incentives, 122 Harv. L. Rev. 1569 (2009)Currently, the elements of a plaintiff’s cause of action for copyright largely follow the tort of trespass to land in that volitional entry (for ...
Gordon, Wendy J.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Probabilities in Probable Cause and Beyond: Statistical Versus Concrete Harms [PDF]

open access: yes, 2010
Colb surfaces the statistical versus concrete harms disparity in judicial (and more broadly, human) reactions to probability-based behavior. In particular, it identifies the disparity in case law that either explicitly relies on the distinction as a ...
Colb, Sherry F.
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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