Results 41 to 50 of about 533,919 (279)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Labour Market Mismatches in the EU and OECD Countries [PDF]

open access: yesRevista Română de Statistică, 2011
The paper discusses labour market mismatches from the perspective of models commonly used for their analysis: matching functions and Beveridge curve.
Gina Cristina DIMIAN
doaj  

Pioneer brand advantage with UK consumers [PDF]

open access: yes, 2002
Telah dilakukan kegiatan Lesson Study (LS) dalam rangka pengembangan kompetensi pendidik bidang biologi di perguruan tinggi untuk agar mengembangkan dan mengimplementasikan pembelajaran biologi yang berorientasi pada character building sekaligus ...
Alpert, Frank   +2 more
core   +4 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

E-portfolio thinking in teacher training: a small-scale study in K-12 in Turkey [PDF]

open access: yes, 2008
The account given in this paper is related to the experiences of foreign language teachers involved in the pilot study undertaken in a high school in Turkey. After outlining the distinctive advantages of e-portfolios in the context of teacher development;
Kok, Ayse
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Methodological approaches to risk assessment of real investment projects

open access: yesMATEC Web of Conferences, 2018
Risk management is impossible without systematically assessing the level of significance of the risks identified in the project. Within the scope of the paper, the distinctive features of various qualitative and quantitative methods for assessing the ...
Bogomolova Ekaterina
doaj   +1 more source

Bioinspired Flexible and Programmable Negative Stiffness Mechanical Metamaterials

open access: yesAdvanced Intelligent Systems, 2023
Energy‐absorbing materials are widely used under certain high‐frequency scenarios, such as cargo packaging or sport protection. Though negative stiffness mechanical metamaterials have many distinctive advantages, fairly low strength and poor specific ...
Xiaojun Tan   +7 more
doaj   +1 more source

Modelling Grocery Retail Topic Distributions: Evaluation, Interpretability and Stability [PDF]

open access: yes, 2020
Understanding the shopping motivations behind market baskets has high commercial value in the grocery retail industry. Analyzing shopping transactions demands techniques that can cope with the volume and dimensionality of grocery transactional data while
Manolopoulou, Ioanna   +4 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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