Results 61 to 70 of about 1,665,556 (298)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Leveraging Distinctive Competency for Competitive Advantages: Mediating of Value Creation and Moderating of Service Innovation in Indonesia's Ferry Transport Companies [PDF]

open access: yes
This study aims to explain how distinctive competency can leverage the competitive advantages of Indonesia’s ferry transport companies, mediated by value creation and moderated by service innovation.
Majid, Suharto Abdul   +4 more
core   +1 more source

Mathematical problems: the advantages of visual strategies [PDF]

open access: yes, 2022
The rapid evolution of today’s world requires that all students have access to an education that values creativity, critical thinking and problem solving.
Vale, Isabel, Barbosa, Ana
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Creating First-Mover Advantages: The Case of Samsung Electronics [PDF]

open access: yes
This paper analyzes the sources of first-mover advantages by examining the case of Samsung Electronics, a firm which has maintained and strengthened the technological leadership in the DRAM industry since 1992.
Jang-Sup SHIN, Sung-Won JANG
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Evolutionary advantages of human hemispheric asymmetries [PDF]

open access: yes, 2009
Hemispheric asymmetries are a basic principle of human brain organization. Once thought to be unique to humans, hemispheric asymmetries have meanwhile been documented in a wide range of species, suggesting they contain an evolutionary advantage. However,
Hirnstein, Marco
core  

Guest Editorial: Methodological Issues in Longitudinal Analyses of Criminal Violence [PDF]

open access: yesInternational Journal of Conflict and Violence, 2015
This guest editorial introduces the Focus Section on Methodological Issues in Longitudinal Analyses of Criminal Violence. Longitudinal designs offer distinctive advantages for purposes of making causal inferences with observational data, but significant
Helmut Thome, Steven F. Messner
doaj  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Eyewitness identification : improving police lineups for suspects with distinctive features [PDF]

open access: yes
Eyewitnesses‘ descriptions of suspects often refer to distinctive facial features, such as tattoos or scars, and the police have to decide how best to create fair lineups in these circumstances.
Zarkadi, Theodora
core  

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