Results 51 to 60 of about 6,315 (180)

Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation

Journal of Orthopaedic Surgery and Research, 2017
Background Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction ...
Qun Zhang, Wei Zhang, Zhuo Zhang, Licheng Zhang, Hua Chen, Ming Hao, Junhao Deng, Peifu Tang   +7 more
doaj   +1 more source

Macrophage piezo1 senses mechanical force to drive osteoclastogenesis via ZBP1: Implications for bone remodelling therapy

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
In the periodontal microenvironment, orthodontic mechanical force activates the mechanosensitive ion channel Piezo1 on macrophages, triggering Ca2+ influx. The increased intracellular Ca2+ concentration drives the upregulation and activation of the innate immune sensor ZBP1, promoting the formation of Z‐NA.
Linlin Zhu, Kejia Zhang, An Song, Weiye Zhao, Yongze Lin, Hao Xu, Zhichun Jin, Yan Wang, Shengnan Wu, Xueyu Sun, Heng Gu, Ming Lu, Hanwen Zhang, Bin Yan   +13 more
wiley   +1 more source

Simulating lateral distraction osteogenesis. [PDF]

PLoS ONE, 2018
Distraction osteogenesis is an effective method for generating large amounts of bone in situ for treating pathologies such as large bone defects or skeletal malformations, for instance leg-length discrepancies.
Frank Niemeyer, Lutz Claes, Anita Ignatius, Nicholaus Meyers, Ulrich Simon   +4 more
doaj   +1 more source

Mechanical Force Promotes Mitochondrial Transfer From Macrophages to BMSCs to Enhance Bone Formation

Cell Proliferation, Volume 59, Issue 5, May 2026.
Mechanical tension activates Drp1‐mediated mitochondrial fission in macrophages, facilitating the release of Mito‐EVs that are subsequently transferred to BMSCs. Additionally, the CD200R‐CD200 interaction enhances the uptake of these mechanically stimulated macrophage‐derived Mito‐EVs by BMSCs, ultimately promoting osteogenic differentiation.
Yingyi Li, Ziwei Yan, Yueming Dai, Hanjia Cai, Yue Chen, Yuyi Chen, Ruofan Jin, Wen Sun, Hua Wang   +8 more
wiley   +1 more source

Scaphoid Nonunion Arthroscopic‐Assisted Reduction and Percutaneous Fixation With Distal Radius Autologous Bone Graft

Arthroscopy Techniques, Volume 15, Issue 4, April 2026.
Abstract Scaphoid fractures are common and often progress to nonunion due to the unique vascularity. When nonunion occurs, patients are at risk of developing carpal collapse and arthritis if not managed appropriately with traditional surgical management.
Anna L. Gorsky, Timothy J. Westbrooks, Kier M. Blevins, Krishna N. Chopra, Nina Suh, Eric R. Wagner   +5 more
wiley   +1 more source

Using an Incidental Separated Segment of the Socket Wall as an Autogenous Block: A Lesson Learned Case Report of Three‐Dimensional Bone Reconstruction in the Anterior Maxilla

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This case report discusses a patient who was referred for the right maxillary central incisor extraction, with subsequent plans for implant replacement and reconstruction of the lateral incisor site. During the extraction of the tooth, a fragment of the distal wall of the socket was fractured.
Mehdi Ekhlasmandkermani, Mohammadreza Talebi Ardakani, Fatemeh Goudarzimoghaddam, Emir Ilkerli   +3 more
wiley   +1 more source

Distraction Osteogenesis for Brachymetatarsia by Using Internal Device

Plastic and Reconstructive Surgery, Global Open, 2017
Summary:. Congenital brachymetatarsia most commonly involves the fourth ray and may be combined with metacarpal shortening. Now, many reports demonstrated the usefulness of distraction osteogenesis for lengthening of the metatarsals by using an external ...
Reina Kitabata, MD, Yoshiaki Sakamoto, MD, Tomohisa Nagasao, MD, Kazuo Kishi, MD   +3 more
doaj   +1 more source

Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 4, April 2026.
ABSTRACT Large‐area bone loss from disease, trauma, or congenital defects requires surgical procedures and bone grafting. Alveolar bone loss from severe periodontal disease and non‐unions often demands immediate grafting. Treating large alveolar bone defects using grafts and substitutes is challenging due to the complex oral environment, infection ...
Allen Zennifer, Sai Sadhananth Srinivasan, Suranji Wijekoon, Sumit Yadav, Sama Abdulmalik, Sangamesh G. Kumbar   +5 more
wiley   +1 more source

Promotion of mandibular distraction osteogenesis by parathyroid hormone via macrophage polarization induced through iNOS downregulation

Heliyon
Objective: To investigate whether Parathyroid hormone (PTH) can promote mandibular distraction osteogenesis by regulating macrophage polarization and the underlying mechanisms of this phenomenon.
Dong-xiang Wang, Zhi-shan Yang, Du-chenhui Li, Yong-di Li, Yu Wang, You-li Chen, Zheng-long Tang   +6 more
doaj   +1 more source

[Distraction osteogenesis in orthopaedics].

Nederlands tijdschrift voor tandheelkunde, 2008
Contains fulltext : 69336.pdf (Publisher’s version ) (Open Access)
Baat, P. de, Baat, C. de, Bessems, J.H.
openaire   +3 more sources