Results 71 to 80 of about 15,609 (223)

The role of bone morphogenetic protein 2 in SMA-directed angiogenesis during distraction osteogenesis [PDF]

, 2016
Bone is one of the few organs capable of regeneration after a substantial injury. As the bone heals itself after trauma, the coupling of angiogenesis to osteogenesis is crucial for the restoration of the skeletal tissue.
Cheng, Thomas Wen-Tao
core   +1 more source

The Use of Recombinant Human Bone Morphogenetic Protein 2 (rhBMP-2) to Promote Spinal Fusion in a Nonhuman Primate Anterior Interbody Fusion Model [PDF]

, 1999
Study Design. A study on the efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in a nonhuman primate anterior interbody fusion model. Objectives.
Fischgrund, Jeffrey S., Harkowitz, Harry N., Hecht, Brian P., Penman, Lori, Shirkhoda, Ali, Toth, Jeffrey M.   +5 more
core   +2 more sources

Mechanical Force Promotes Mitochondrial Transfer From Macrophages to BMSCs to Enhance Bone Formation

Cell Proliferation, Volume 59, Issue 5, May 2026.
Mechanical tension activates Drp1‐mediated mitochondrial fission in macrophages, facilitating the release of Mito‐EVs that are subsequently transferred to BMSCs. Additionally, the CD200R‐CD200 interaction enhances the uptake of these mechanically stimulated macrophage‐derived Mito‐EVs by BMSCs, ultimately promoting osteogenic differentiation.
Yingyi Li, Ziwei Yan, Yueming Dai, Hanjia Cai, Yue Chen, Yuyi Chen, Ruofan Jin, Wen Sun, Hua Wang   +8 more
wiley   +1 more source

Femoral nonunion with segmental bone defect treated by distraction osteogenesis with monolateral external fixation

Journal of Orthopaedic Surgery and Research, 2017
Background Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction ...
Qun Zhang, Wei Zhang, Zhuo Zhang, Licheng Zhang, Hua Chen, Ming Hao, Junhao Deng, Peifu Tang   +7 more
doaj   +1 more source

Method for Automated Bone Shape Correction within Bone Distraction Procedure [PDF]

, 2016
The method for automated bone shape correction within bone distraction procedure is presented. High precision deformation angle measurement is provided by the software for X-Ray images processing. Special BDC v.1.0.1. application is designed. The purpose
Blynsky, Fedor Yuryevich
core   +1 more source

Using an Incidental Separated Segment of the Socket Wall as an Autogenous Block: A Lesson Learned Case Report of Three‐Dimensional Bone Reconstruction in the Anterior Maxilla

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This case report discusses a patient who was referred for the right maxillary central incisor extraction, with subsequent plans for implant replacement and reconstruction of the lateral incisor site. During the extraction of the tooth, a fragment of the distal wall of the socket was fractured.
Mehdi Ekhlasmandkermani, Mohammadreza Talebi Ardakani, Fatemeh Goudarzimoghaddam, Emir Ilkerli   +3 more
wiley   +1 more source

Simulating lateral distraction osteogenesis. [PDF]

PLoS ONE, 2018
Distraction osteogenesis is an effective method for generating large amounts of bone in situ for treating pathologies such as large bone defects or skeletal malformations, for instance leg-length discrepancies.
Frank Niemeyer, Lutz Claes, Anita Ignatius, Nicholaus Meyers, Ulrich Simon   +4 more
doaj   +1 more source

Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 4, April 2026.
ABSTRACT Large‐area bone loss from disease, trauma, or congenital defects requires surgical procedures and bone grafting. Alveolar bone loss from severe periodontal disease and non‐unions often demands immediate grafting. Treating large alveolar bone defects using grafts and substitutes is challenging due to the complex oral environment, infection ...
Allen Zennifer, Sai Sadhananth Srinivasan, Suranji Wijekoon, Sumit Yadav, Sama Abdulmalik, Sangamesh G. Kumbar   +5 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, Volume 4, Issue 1, March 2026.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Treatment of severe micrognathia in an adult with distraction osteogenesis: A case report

Clinical Case Reports, 2023
Key Clinical Message Distraction osteogenesis (DO) of the mandible is often performed at a young age, and there are few reports after age 30, as in this case.
Katsuhisa Sekido, Kumiko Fujiwara, Hidetake Tachinami, Shuichi Imaue, Keishi Hanashiro, Makoto Noguchi   +5 more
doaj   +1 more source