Results 61 to 70 of about 6,315 (180)

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, Volume 4, Issue 1, March 2026.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Distraction force promotes the osteogenic differentiation of Gli1+ cells in facial sutures via primary cilia-mediated Hedgehog signaling pathway

Stem Cell Research & Therapy
Background Trans-sutural distraction osteogenesis (TSDO) involves the application of distraction force to facial sutures to stimulate osteogenesis. Gli1+ cells in the cranial sutures play an important role in bone growth.
Mengying Jin, Yang An, Zheng Wang, Guanhuier Wang, Zhiyu Lin, Pengbing Ding, Enhang Lu, Zhenmin Zhao, Hongsen Bi   +8 more
doaj   +1 more source

Clinical application of mandibular distraction osteogenesis

Kouqiang hemian waike zazhi
Distraction osteogenesis (DO) is a surgical technique that promotes new bone formation by gradually pulling apart bone segments using a specialized distraction device.
JIANG Nan, ZHU Songsong
doaj   +1 more source

Cephalometric evaluation of patients treated by maxillary anterior segmental distraction

Journal of Cleft Lip Palate and Craniofacial Anomalies, 2018
Background: Maxillary hypoplasia secondary to repaired cleft lips and palates is common. The extent of hypoplasia is dependent on several factors. It is not possible to correct maxillary hypoplasia by conventional orthodontics and relapse is common after
Shanahaz Kuzhippayi Saidalavi, Balakrishna Shetty, Goutham Reddy, Sunil Muddaiah, Sanju Somaiah, Roopa Sidde Gowda   +5 more
doaj   +1 more source

Corrected Cephalometric Analysis to Determine the Distance and Vector of Distraction Osteogenesis for Syndromic Craniosynostosis

Plastic and Reconstructive Surgery, Global Open, 2017
Background:. The purpose of this study was to confirm the utility of a corrected cephalometric analysis to facilitate the planning of distraction osteogenesis with Le Fort III osteotomy for syndromic craniosynostosis. Methods:.
Shinji Kobayashi, MD, Toshihiko Fukawa, DDS, Takashi Hirakawa, DDS, Toshihiko Satake, MD, Jiro Maegawa, MD   +4 more
doaj   +1 more source

Mechanotransduction and musculoskeletal regeneration: Molecular mechanisms and interdisciplinary applications

Genes and Diseases
Distraction osteogenesis, or the Illizarov technique, induces bone regeneration using distractive mechanical forces. Nevertheless, Wolff's law holds that bone adapts to reverse compressive mechanical loads, growing denser in areas of high pressure and ...
Xiajie Huang, Wenjun Hao, Yangzhou Mo, Xinyun Liang, Xiaomei Wu, Daofu Zeng, Yubin Mo, William Lu, Di Chen, Yan Chen   +9 more
doaj   +1 more source

Treatment of post-traumatic elbow deformities in children with the Ilizarov distraction osteogenesis technique

Acta Orthopaedica et Traumatologica Turcica, 2017
Objective: The present study assessed functional and radiographic outcomes of distraction osteogenesis treatment of post-traumatic elbow deformities in children.
Cenk Özkan, Mehmet Ali Deveci, Mustafa Tekin, Ömer Sunkar Biçer, Kadir Gökçe, Mahir Gülşen   +5 more
doaj   +1 more source

Bone regeneration during osteoporosis: a translational in vivo monitoring of callus mechanical parameters

Frontiers in Bioengineering and Biotechnology
IntroductionRegenerating osteoporotic bone remains challenging due to healing complications such as non-unions. Distraction osteogenesis is a promising technique for bone repair, but its efficacy under osteoporotic conditions is poorly understood.
Juan J. Toscano-Angulo, Juan Mora-Macías, Pablo Blázquez-Carmona, Manuel Sánchez-Raya, Juan Morgaz, Juan Antonio Gómez-Galán, M. M. Granados, Jaime Domínguez, Esther Reina-Romo   +8 more
doaj   +1 more source

The biology of bone lengthening

Journal of Children's Orthopaedics, 2016
Distraction osteogenesis biologically resembles fracture healing with distinctive characteristics notably in the distraction phase of osteogenesis. In the latency phase of bone lengthening, like in the inflammatory phase of fracture repair, interleukines
Ivan Hvid, Joachim Horn, Stefan Huhnstock, Harald Steen   +3 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source