Results 81 to 90 of about 26,832 (297)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

State of the Art in Parallel Computing with R [PDF]

R is a mature open-source programming language for statistical computing and graphics. Many areas of statistical research are experiencing rapid growth in the size of data sets. Methodological advances drive increased use of simulations.
Hao Yu, Martin Morgan, Markus Schmidberger, Ulrich Mansmann, Luke Tierney, Dirk Eddelbuettel   +5 more
core  

A grid-based virtual reactor : parallel performance and adaptive load balancing

, 2007
We address the problem of porting parallel distributed applications from static homogeneous cluster environments to dynamic heterogeneous Grid resources.
Korkhov, Vladimir V., Sloot, Peter M. A., Krzhizhanovskaya, Valeria V.   +2 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Parallel algorithm to find Bayes-Nash solution to the bimatrix informational extended game [PDF]

Computer Science Journal of Moldova, 2018
We propose to use the new methodology for solving the complete and perfect information bimatrix game. To solve the games of these type we construct the incomplete and imperfect information game generated by the informational extended strategies.
Boris Hancu, Anatolie Gladei
doaj  

A Spark-Based Parallel Fuzzy $c$ -Means Segmentation Algorithm for Agricultural Image Big Data

IEEE Access, 2019
With the explosive growth of image big data in the agriculture field, image segmentation algorithms are confronted with unprecedented challenges. As one of the most important images segmentation technologies, the fuzzy c-means (FCMs) algorithm has been ...
Bin Liu, Songrui He, Dongjian He, Yin Zhang, Mohsen Guizani   +4 more
doaj   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

An Asymptotic Ensemble Learning Framework for Big Data Analysis

IEEE Access, 2019
In order to enable big data analysis when data volume goes beyond the available computing resources, we propose a new method for big data analysis. This method uses only a few random sample data blocks of a big data set to obtain approximate results for ...
Salman Salloum, Joshua Zhexue Huang, Yulin He, Xiaojun Chen   +3 more
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Raspberry Pi Cluster for Parallel and Distributed Computing [PDF]

, 2019
Parallel and distributed computing have become an essential part of the ‘Big Data’ processing and analysis, especially for geophysical applications.
Ha, Ngoc
core   +1 more source