Results 91 to 100 of about 1,076,339 (338)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Multimodal Technologies and Interaction, 2020 In recent years, the employment of behavior models to motivate behavior change has become a global trend in fitness application design. However, there is hardly any large-scale study of these applications to understand users’ exercise-type preferences ...
Kiemute Oyibo, Julita Vassileva
doaj +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Analysis of Mobile Edge Computing for Vehicular Networks
Sensors, 2019 Vehicular ad-hoc Networks (VANETs) are an integral part of intelligent transportation systems (ITS) that facilitate communications between vehicles and the internet.
Zachary W. Lamb, Dharma P. Agrawal
doaj +1 more source
Multimodal Technologies and Interaction, 2020 Fitness apps equipped with various persuasive features have become popular worldwide due to the physical inactivity crisis. However, there is a limited understanding of the most important persuasive features that drive their adoption and the moderating ...
Kiemute Oyibo, Julita Vassileva
doaj +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Simple Distributed Weighted Matchings [PDF]
arXiv, 2004 Wattenhofer [WW04] derive a complicated distributed algorithm to compute a weighted matching of an arbitrary weighted graph, that is at most a factor 5 away from the maximum weighted matching of that graph. We show that a variant of the obvious sequential greedy algorithm [Pre99], that computes a weighted matching at most a factor 2 away from the ...
arxiv
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Smart systems, the fourth industrial revolution and new challenges in distributed computing [PDF]
2018, 2019 Smart systems and the smart world concept are addressed in the framework of the fourth industrial revolution. New challenges in distributed autonomous robots and computing are considered. An illustration of a new kind of smart and reconfigurable distributed modular robot system is given.
arxiv
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source