Results 101 to 110 of about 3,460,543 (299)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Adaptive Energy-Aware Computation Offloading for Cloud of Things Systems

open access: yesIEEE Access, 2017
Cloud computing has become the de facto computing platform for application processing in the era of the Internet of Things (IoT). However, limitations of the cloud model, such as the high transmission latency and high costs are giving birth to a new ...
Yucen Nan   +6 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Supervised Distributed Computing

open access: yes
We introduce a new framework for distributed computing that extends and refines the standard master-worker approach of scheduling multi-threaded computations. In this framework, there are different roles: a supervisor, a source, a target, and a collection of workers.
John Augustine 0001   +2 more
openaire   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Computing for construals in distributed participatory design : principles and tools [PDF]

open access: yes, 2009
Distributed participatory design aspires to standards of inclusivity and humanity in introducing technology to the workplace that are hard to attain. The demands it makes upon the development and use of computing technology are particularly topical, as ...
Beynon, Meurig, Chan, Zhan En
core  

Video Analytics in Elite Soccer: A Distributed Computing Perspective. [PDF]

open access: yesProc IEEE Sens Array Multichannel Signal Process Workshop, 2022
Jha D   +6 more
europepmc   +1 more source

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