Results 91 to 100 of about 3,460,543 (299)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Academic and Distributed Computing Services Short Course Bulletin, Fall 1996
, 1996 University of Minnesota. Academic and Distributed Computing Services. (1996). Academic and Distributed Computing Services Short Course Bulletin, Fall 1996.
University of Minnesota. Academic and Distributed Computing Services
core
Analysis of Mobile Edge Computing for Vehicular Networks
Sensors, 2019 Vehicular ad-hoc Networks (VANETs) are an integral part of intelligent transportation systems (ITS) that facilitate communications between vehicles and the internet.
Zachary W. Lamb, Dharma P. Agrawal
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Academic and Distributed Computing Services Short Course Bulletin, Summer 1996
, 1996 University of Minnesota. Academic and Distributed Computing Services. (1996). Academic and Distributed Computing Services Short Course Bulletin, Summer 1996.
University of Minnesota. Academic and Distributed Computing Services
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Academic and Distributed Computing Services Training Bulletin, Spring 1998
, 1998 University of Minnesota. Academic and Distributed Computing Services. (1998). Academic and Distributed Computing Services Training Bulletin, Spring 1998.
University of Minnesota. Academic and Distributed Computing Services
core
Knowledge Services for Distributed Service Integration [PDF]
, 2002 Key Objectives: Introduce a service-oriented approach to providing knowledge support for distributed computing, develop a generic knowledge service architecture to realise such an approach, apply this approach design search and optimisation (Geodise) to ...
Chen, L. +9 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Modeling Implicit Trust in Matrix Factorization-Based Collaborative Filtering
Applied Sciences, 2019 Recommendation systems often use side information to both alleviate problems, such as the cold start problem and data sparsity, and increase prediction accuracy.
Yuyu Yuan, Ahmed Zahir, Jincui Yang
doaj +1 more source