Results 81 to 90 of about 1,612,633 (296)

On Distributed Computing with Beeps

CoRR, 2015
We consider networks of processes which interact with beeps. Various beeping models are used. The basic one, defined by Cornejo and Kuhn [CK10], assumes that a process can choose either to beep or to listen; if it listens it can distinguish between silence or the presence of at least one beep.
Yves Métivier, John Michael Robson, Akka Zemmari   +2 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Non-Local Probes Do Not Help with Graph Problems

, 2015
This work bridges the gap between distributed and centralised models of computing in the context of sublinear-time graph algorithms. A priori, typical centralised models of computing (e.g., parallel decision trees or centralised local algorithms) seem to
Göös, Mika, Hirvonen, Juho, Levi, Reut, Medina, Moti, Suomela, Jukka   +4 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

MEFL: Meta-Equilibrize Federated Learning for Imbalanced Data in IoT

Entropy
In the Internet of Things (IoT), data distribution among diverse terminals exhibits substantial statistical heterogeneity. This imbalance can lead to skewness and accuracy degradation, ultimately affecting the generalization ability and robustness of ...
Jialu Tang, Yali Gao, Xiaoyong Li, Jia Jia   +3 more
doaj   +1 more source

Fast Distributed PageRank Computation

, 2015
Over the last decade, PageRank has gained importance in a wide range of applications and domains, ever since it first proved to be effective in determining node importance in large graphs (and was a pioneering idea behind Google's search engine).
Andersen, Anisur Rahaman Molla, Atish Das Sarma, Avrachenkov, Bahmani, Bahmani, Berkhin, Bianchini, Brin, Cook, Das Sarma, Das Sarma, Das Sarma, Eli Upfal, Gopal Pandurangan, Grolmusz, Iván, Langville, Mitzenmacher, Page, Perra, Sankaralingam, Shi, Wang   +23 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Detecting and Tracing i.i.d. Attacks in Networks With Any Number of Relays

IEEE Access, 2016
This paper investigates the detection and tracing problems in a multi-relay network, where a source wants to exchange the information with a destination through multiple potential malicious relay nodes.
Ruohan Cao, Shanguo Huang, Yueming Lu
doaj   +1 more source