Results 81 to 90 of about 1,610,469 (333)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

MEFL: Meta-Equilibrize Federated Learning for Imbalanced Data in IoT

Entropy
In the Internet of Things (IoT), data distribution among diverse terminals exhibits substantial statistical heterogeneity. This imbalance can lead to skewness and accuracy degradation, ultimately affecting the generalization ability and robustness of ...
Jialu Tang, Yali Gao, Xiaoyong Li, Jia Jia   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Detecting and Tracing i.i.d. Attacks in Networks With Any Number of Relays

IEEE Access, 2016
This paper investigates the detection and tracing problems in a multi-relay network, where a source wants to exchange the information with a destination through multiple potential malicious relay nodes.
Ruohan Cao, Shanguo Huang, Yueming Lu
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Survey of Distributed Decision [PDF]

, 2016
We survey the recent distributed computing literature on checking whether a given distributed system configuration satisfies a given boolean predicate, i.e., whether the configuration is legal or illegal w.r.t. that predicate.
Feuilloley, Laurent, Fraigniaud, Pierre
core   +3 more sources

A Hierarchical Framework of Cloud Resource Allocation and Power Management Using Deep Reinforcement Learning

, 2017
Automatic decision-making approaches, such as reinforcement learning (RL), have been applied to (partially) solve the resource allocation problem adaptively in the cloud computing system.
Li, Zhe, Lin, Sheng, Liu, Ning, Qiu, Qinru, Tang, Jian, Wang, Yanzhi, Xu, Jielong, Xu, Zhiyuan   +7 more
core   +1 more source

Retraction Note: Research on North Gulf distributed big data submarine 3D terrain computing system based on remote sensing and multi-beam [PDF]

, 2022
Yuan Dong, Baoqing Hu, Shilun Zhang, Yuanlin Huang, GuoCai Nong, Xin Han   +5 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Analysis of Mobile Edge Computing for Vehicular Networks

Sensors, 2019
Vehicular ad-hoc Networks (VANETs) are an integral part of intelligent transportation systems (ITS) that facilitate communications between vehicles and the internet.
Zachary W. Lamb, Dharma P. Agrawal
doaj   +1 more source