Results 121 to 130 of about 24,460,921 (337)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Distributed Control Synthesis

EPiC Series in Computing, 2018
Synthesis of control for distributed systems is considered to be undecidable problem, under the assumption that control is performed by supervisors syncrhonizing with the original processes and selectively blocking or supporting the enabled transitions.
Doron Peled, Sven Schewe
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Alternative audio-graphic method for presenting structural information in mathematical graphs designed for low-vision users

Scientific Reports
Despite advances in assistive technologies, existing tools for teaching mathematics to students with low vision often fail to effectively convey structural information in graphs and function plots.
Ewa Dzierzgowska, Michał Maćkowski, Mateusz Kawulok, Piotr Brzoza, Stella Maćkowska, Dominik Spinczyk   +5 more
doaj   +1 more source

Distributed control for geometric pattern formation of large-scale multirobot systems. [PDF]

Front Robot AI, 2023
Giusti A, Maffettone GC, Fiore D, Coraggio M, di Bernardo M.   +4 more
europepmc   +1 more source

Distributed control for COFS 1 [PDF]

An overview is given of the work being done at NASA LaRC on developing the Control of Flexible Structures (COFS) 1 Flight Experiment Baseline Control Law. This control law currently evolving to a generic control system software package designed to supply
Lindner, D. K., Montgomery, R. C., Sulla, Jeff   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Scalable Distributed Control Algorithm for Bearing-Only Passive UAV Formation Maintenance. [PDF]

Sensors (Basel), 2023
Gao Y, Feng H, Chen J, Li J, Wei Z.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Open-source lower controller for twelve degrees of freedom hydraulic quadruped robot with distributed control scheme. [PDF]

HardwareX, 2023
Fang L, Zhang J, Zong H, Wang X, Zhang K, Shen J, Lu Z.   +6 more
europepmc   +1 more source