Results 51 to 60 of about 2,116,890 (336)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
State of the art and future research on distributed processing system in Internet environment
大数据, 2018 Due to the gradual failure of Moore’s law,traditional centralized data processing systems begin to show performance bottlenecks,which can’t effectively support the rapid development of current business.At the same time,due to the security,cost,policy and
Pengwei MA, Kai WEI, Chunyu JIANG
doaj
XML Gateway for Heterogeneous Distributed Database Management Systems
JISR Management and Social Sciences & Economics, 2004 Conventional standalone application development paradigm is being transformed into multi-layered application development process. The main reason of transformation is the execution environment— particularly internetworking.
Aslam Parvez Memon, Muhammad Nadeem
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Distributed Database Using Mobile Agent [PDF]
, 2012 The number of sources of information brings several problems, among them about how to combine the distributed data storage and different. Information on an organization or company is usually stored in separate locations and different formats.
Hartati, S. (Sri) +3 more
core
Cross-middleware Interoperability in Distributed Concurrent Engineering
, 2007 Secure, distributed collaboration between different organizations is a key challenge in Grid computing today. The GDCD project has produced a Grid-based demonstrator Virtual Collaborative Facility (VCF) for the European Space Agency.
Leonard, Thomas +3 more
core +1 more source
Xibei Gongye Daxue XuebaoWith the continuous development of information technology, distributed database has become a research hotspot. Due to the limit support for SQL and defects in transaction processing and consistency of distributed databases based on NoSQL architecture ...
DU Yide, LIU Wenjie
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source