Results 61 to 70 of about 11,569,212 (291)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Operator parallel optimization strategy for distributed databases
Xibei Gongye Daxue XuebaoWith the continuous development of network technology, the scale of data has shown explosive growth, which leads gradually to replacing traditional single machine databases with distributed databases.
LIU Wenjie, LYU Jingchao
doaj +1 more source
Flexible Resolution of Authorisation Conflicts in Distributed Systems [PDF]
, 2008 Flexible Resolution of Authorisation Conflicts in Distributed ...
Giovanni Russello +10 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
State of the art and future research on distributed processing system in Internet environment
大数据, 2018 Due to the gradual failure of Moore’s law,traditional centralized data processing systems begin to show performance bottlenecks,which can’t effectively support the rapid development of current business.At the same time,due to the security,cost,policy and
Pengwei MA, Kai WEI, Chunyu JIANG
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Distributed Database Systems in Vehicular Ad-Hoc Network
Communications, 2010 The article introduces basics of classic Distributed Database System (DDBS) and explains its unsuitability for dynamically changing networks such as Vehicular Ad-hoc Network (VANET). Thus a concept of a new architecture is proposed. This new architecture
Jan Janech, Tomas Baca
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Component Approach to Software Development for Distributed Multi-Database System [PDF]
The paper deals with a component based approach for software development in a distributed environment for the database retrieval operations. A Core Component for a distributed multi-database system has been proposed.
Vijayakumar BALAKRISHNAN +2 more
core
Performance analysis of static locking in replicated distributed database systems [PDF]
, 1991 Data replication and transaction deadlocks can severely affect the performance of distributed database systems. Many current evaluation techniques ignore these aspects, because it is difficult to evaluate through analysis and time consuming to evaluate ...
Kuang, Yinghong, Mukkamala, Ravi
core