Results 61 to 70 of about 5,454,291 (247)
Enhanced adaptive partitioning in a distributed graph database
Journal of Information and Telecommunication, 2021 Nowadays, open-source graph databases do not include an inherent mechanism for data relocation that would be based on their usage. They often do not offer even appropriate monitoring that could help to make such a decision.
Lucie Svitáková +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A grid-based infrastructure for distributed retrieval [PDF]
, 2009 In large-scale distributed retrieval, challenges of latency, heterogeneity, and dynamicity emphasise the importance of infrastructural support in reducing the development costs of state-of-the-art solutions.
Sibeko, M. +9 more
core +4 more sources
Operator parallel optimization strategy for distributed databases
Xibei Gongye Daxue XuebaoWith the continuous development of network technology, the scale of data has shown explosive growth, which leads gradually to replacing traditional single machine databases with distributed databases.
LIU Wenjie, LYU Jingchao
doaj +1 more source
Mobile Collaborative Information System Using Distributed Database Architecture [PDF]
, 2009 This thesis examines the feasibility of communal information sharing between mobile devices using a distributed architecture for the underlying database topology, through research aimed at satisfying two primary objectives: i.
Cato, D. C.
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
State of the art and future research on distributed processing system in Internet environment
大数据, 2018 Due to the gradual failure of Moore’s law,traditional centralized data processing systems begin to show performance bottlenecks,which can’t effectively support the rapid development of current business.At the same time,due to the security,cost,policy and
Pengwei MA, Kai WEI, Chunyu JIANG
doaj
Cyclic Distributed Garbage Collection with Group Merger [PDF]
, 1997 This paper presents a new algorithm for distributed garbage collection and outlines its implementation within the Network Objects system. It supersedes the earlier version, /pubs/1997/548. The algorithm is based on a reference listing scheme augmented by
Helena Rodrigues +5 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source