Results 61 to 70 of about 574,204 (308)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Evolutionary algorithms for allocating data in distributed database systems
, 2002 A major cost in executing queries in a distributed database system is the data transfer cost incurred in transferring relations (fragments) accessed by a query from different sites to the site where the query is initiated.
Kwok, YK +5 more
core +1 more source
Operator parallel optimization strategy for distributed databases
Xibei Gongye Daxue XuebaoWith the continuous development of network technology, the scale of data has shown explosive growth, which leads gradually to replacing traditional single machine databases with distributed databases.
LIU Wenjie, LYU Jingchao
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Verification of Liveness Properties in Distributed Systems
, 2009 This paper presents liveness properties that need to be preserved by Event-B models of distributed systems. Event-B is a formal technique for development of models of distributed systems related via refinement.
Yadav, Divakar +3 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
State of the art and future research on distributed processing system in Internet environment
大数据, 2018 Due to the gradual failure of Moore’s law,traditional centralized data processing systems begin to show performance bottlenecks,which can’t effectively support the rapid development of current business.At the same time,due to the security,cost,policy and
Pengwei MA, Kai WEI, Chunyu JIANG
doaj
Distributed Database Systems in Vehicular Ad-Hoc Network
Communications, 2010 The article introduces basics of classic Distributed Database System (DDBS) and explains its unsuitability for dynamically changing networks such as Vehicular Ad-hoc Network (VANET). Thus a concept of a new architecture is proposed. This new architecture
Jan Janech, Tomas Baca
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source