Results 51 to 60 of about 5,454,291 (247)
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
DRAS-TIC Linked Data: Evenly Distributing the Past
Memory institutions must be able to grow a fully-functional repository incrementally as collections grow, without expensive enterprise storage, massive data migrations, and the performance limits that stem from the vertical storage strategies.
Gregory Jansen +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Rigorous Design of Fault-Tolerant Transactions for Replicated Database Systems using Event B
System availability is improved by the replication of data objects in a distributed database system. However, during updates, the complexity of keeping replicas identical arises due to failures of sites and race conditions among conflicting transactions.
Yadav, Divakar, Butler, Michael
core +1 more source
FEEDBACK ON A PUBLICLY DISTRIBUTED IMAGE DATABASE: THE MESSIDOR DATABASE
The Messidor database, which contains hundreds of eye fundus images, has been publicly distributed since 2008. It was created by the Messidor project in order to evaluate automatic lesion segmentation and diabetic retinopathy grading methods.
Etienne Decencière +11 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
With the continuous development of information technology, distributed database has become a research hotspot. Due to the limit support for SQL and defects in transaction processing and consistency of distributed databases based on NoSQL architecture ...
DU Yide, LIU Wenjie
doaj +1 more source
Formal Development of a Total Order Broadcast for Distributed Transactions using Event-B
. In a replicated database system, copies of the database are kept across several sites for fault-tolerance and availability. Data access in such systems is usually done within a transactional framework.
Yadav, Divakar +3 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Allocation Fragments of the Distributed Database
The paper describes the distribution fragments of the database under a mathematical model with criterial function involving the influence of the Transaction and Concurrency proccesing in Database systems. The model could solve variants for replication of
Karol Matiasko
doaj +1 more source

