Results 81 to 90 of about 574,204 (308)
A grid-based infrastructure for distributed retrieval
, 2007 In large-scale distributed retrieval, challenges of latency, heterogeneity, and dynamicity emphasise the importance of infrastructural support in reducing the development costs of state-of-the-art solutions.
Fabio Crestani +19 more
core +1 more source
Record matching method based on local CON model in distributed database
Tongxin xuebao, 2011 For existing record matching methods needed much artificial participation of experts or depend on heuristic rules heavily,and they could not handle the problem of large-scale data,A record matching method based on the local CON model was proposed.The ...
LI Jiao1 +3 more
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
GEOBARN: A Practical Grid Geospatial Database System
Advances in Electrical and Computer Engineering, 2009 Recently, more and more geospatial data are generated and distributed with the promising data acquirement techniques like satellite imaging and digital cartography.
XIE, X., FANG, Y., HUANG, Z., PAN, M.
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Self-organizing distributed workflow management [PDF]
, 2015 The proliferation of service-oriented architectures in the last decade has brought forward an important class of sophisticated distributed applications that are founded on the idea of composing multiple simple services into a complex, coherent whole ...
Stojnic, Nenad
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Design of a Distributed Database for Doctoral Studies Management [PDF]
This paper aims to create a system that manages doctoral school requirements. The management of doctoral school implies administration of information like PhD personal information, Supervisors, Teachers, and other information that may be useful.
Aurelian Razvan COSTIN +1 more
core +1 more source
Database Consistency Using Update-Ordering in Distributed Databases
Journal of Algorithms & Computational Technology, 2007 Database consistency is one of the major issues in replicated database in distributed database systems. The logical design for the replicated nodes and the transaction management mechanism are two aspects that give a serious impact to the performance and
W. N. Shuhadah +4 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source