Results 101 to 110 of about 11,569,212 (291)
Semi-Distributed Vacuuming Model on Temporal Database (SDVMT) [PDF]
Database Systems Journal, 2012 Temporal database is one of the most common types of databases. Portfolio management, accounting, storage, treatment management systems, aerology systems and scheduling are applications which their data have time references.
Mohammad Shabanali FAMI +3 more
doaj
Evolutionary algorithms for allocating data in distributed database systems
, 2002 A major cost in executing queries in a distributed database system is the data transfer cost incurred in transferring relations (fragments) accessed by a query from different sites to the site where the query is initiated.
Kwok, YK +5 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
A Distributed Scientific Data Archive Using the Web, XML and SQL/MED
, 1999 We have developed a web-based architecture and user interface for fast storage, searching and retrieval of large, distributed, files resulting from scientific simulations.
Nicole, Denis A +3 more
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
PERMISSION RESTRICTION METHOD AND ALGORITHM IN DISTRIBUTED DATABASE
, 2023 The article analyzes the distributed database architecture, permission management methods, existing threats and vulnerabilities in the distributed database, features of permission restriction and their application in the distributed database, Role-based ...
Sadikov Sh.M.
core
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Rigorous Design of Distributed Transactions
Database replication is traditionally envisaged as a way of increasing fault-tolerance and availability. It is advantageous to replicate the data when transaction workload is predominantly read-only.
Yadav, Divakar
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source