Results 91 to 100 of about 6,753,331 (375)

The Semi-join Query Optimization In Distributed Database System

open access: yesInformation Technology Convergence and Services, 2012
In distributed database system, the distributed deposition and redundancy data brought convenient to fault recovery, but they make distributed query processing more complicated at the same time.
Lina Zhou   +3 more
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Development of a distributed knowledge-based system [PDF]

open access: yes, 2001
This paper describes the development of a distributed knowledge-based system. A software system, namely Distributed Algorithmic and Rule-based Blackboard System (DARBS), was developed from its predecessor ARBS, which lacked the distributed computing ...
Hopgood, AA, Nolle, L, Wong, KCP
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Component Approach to Software Development for Distributed Multi-Database System [PDF]

open access: yes
The paper deals with a component based approach for software development in a distributed environment for the database retrieval operations. A Core Component for a distributed multi-database system has been proposed.
Muthaiyan MADIAJAGAN   +2 more
core  

Using the IMEDS distributed database for epidemiological studies in type 2 diabetes mellitus. [PDF]

open access: yesBMJ Open Diabetes Res Care, 2022
Huang TY   +15 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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