Results 71 to 80 of about 2,641,244 (300)

Normalization of equation with linear distributed delay

open access: yesМоделирование и анализ информационных систем, 2009
Some properties of the dynamics of a differential equation with the linear distributed delay is studied. In critical cases, which all have an infinite dimension, special equations - normal forms - were built.
I. S. Kashchenko
doaj  

Qualitative Analysis of a Model of Renewable Resources and Population with Distributed Delays

open access: yesMathematics, 2022
This work generalizes Matsumoto et al.’s dynamic model of population and renewable resources by substituting a distributed delay for the time delay. It is proved that the equilibrium point may lose or gain local stability, allowing for the observation of
Tiziana Ciano   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

MeshTree: A Delay optimised Overlay Multicast Tree Building Protocol [PDF]

open access: yes, 2005
We study decentralised low delay degree-constrained overlay multicast tree construction for single source real-time applications. This optimisation problem is NP-hard even if computed centrally.
Waters, A. Gill   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Experimental time-delayed feedback control with variable and distributed delays [PDF]

open access: yesPhysical Review E, 2012
We report on several improvements of the classical time-delayed feedback control method for stabilization of unstable periodic orbits or steady states. In an electronic circuit experiment, we were able to realize time-varying and distributed delays in the control force leading to successful control for large parameter sets, including large time delays.
Jüngling, Thomas   +2 more
openaire   +3 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Oscillation of equations with an infinite distributed delay

open access: yesComputers & Mathematics with Applications, 2010
The authors are concerned with the problem of existence, to integrodifferential equations of the form \[ \dot x(t)+ \int^t_{-\infty} x(s) d_s R(t, s)= f(t),\quad t> t_0, \] of nonoscillatory solutions on \([0,\infty)\). The usual initial data are admitted: \[ x(t)= \varphi(t),\quad t< t_0,\quad x(t_0)= x_0.
Leonid Berezansky, Elena Braverman
openaire   +1 more source

Distributed supervisory control of discrete-event systems with communication delay [PDF]

open access: yes, 2015
This paper identifies a property of delay-robustness in distributed supervisory control of discrete-event systems (DES) with communication delays. In previous work a distributed supervisory control problem has been investigated on the assumption that ...
Cai, Kai   +3 more
core   +1 more source

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