Results 71 to 80 of about 248,923 (267)

The Perron Condition for Delayed Systems with Caputo Fractional Derivatives

open access: yesMathematics
In the present work, we study a class of nonhomogeneous linear systems with fractional derivatives in Caputo’s sense of incommensurate order and distributed delays, satisfying the Perron condition.
Hristo Kiskinov   +3 more
doaj   +1 more source

Dynamical Models For Prices With Distributed Delays

open access: yesTimisoara Journal of Economics and Business, 2015
Abstract In the present paper we study some models for the price dynamics of a single commodity market. The quantities of supplied and demanded are regarded as a function of time. Nonlinearities in both supply and demand functions are considered. The inventory and the level of inventory are taken into consideration.
Gabriela MIRCEA   +2 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

pth moment exponential stability of stochastic fuzzy Cohen–Grossberg neural networks with discrete and distributed delays

open access: yesNonlinear Analysis, 2017
In this paper, stochastic fuzzy Cohen–Grossberg neural networks with discrete and distributed delays are investigated. By using Lyapunov function and the Ito differential formula, some sufficient conditions for the pth moment exponential stability of ...
Changjin Xu, Peiluan Li
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Mathematical Models of Epidemics with Infection Time

open access: yesAppliedMath
After an infectious contact, there is a time lapse before the individual actually becomes infected. In this paper, we present different ways of incorporating this incubation or infection time into epidemic mathematical models. For simplicity, we consider
Benito Chen-Charpentier
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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