Results 81 to 90 of about 2,641,244 (300)

Spatiotemporal Dynamics of a Generalized Viral Infection Model with Distributed Delays and CTL Immune Response

open access: yesComputation, 2019
In this paper, we propose and investigate a diffusive viral infection model with distributed delays and cytotoxic T lymphocyte (CTL) immune response.
Khalid Hattaf
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Fundamental Matrix, Measure Resolvent Kernel and Stability Properties of Fractional Linear Delayed System with Discontinuous Initial Conditions

open access: yesMathematics
In the present work, a Cauchy (initial) problem for a fractional linear system with distributed delays and Caputo-type derivatives of incommensurate order is considered.
Hristo Kiskinov   +3 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Delayed Energy Demand–Supply Models with Gamma-Distributed Memory Kernels

open access: yesAppliedMath
The stability of energy demand–supply systems is often affected by delayed feedback caused by regulatory inertia, communication lags, and heterogeneous agent responses.
Carlo Bianca   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Oscillation for equations with positive and negative coefficients and distributed delay II: Applications

open access: yesElectronic Journal of Differential Equations, 2003
We apply the results of our previous paper "Oscillation of equations with positive and negative coefficients and distributed delay I: General results" to the study of oscillation properties of equations with several delays and positive and negative ...
Leonid Berezansky, Elena Braverman
doaj  

A Projection Neural Network With Delays and Optimization Approaches for Solving Absolute Value Equations

open access: yesIEEE Access
This paper proposes a projection neural network with delays, including discrete and distributed delay, for solving absolute value equations of the form $Ax-\vert x\vert = b$ .
Kiattisak Prathom   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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