Exponential input‐to‐state stability of delay reaction‐diffusion systems
This brief paper considers the exponential input‐to‐state stability (EISS) for delay reaction‐diffusion systems (DRDSs). The distributed input and boundary input are both included in the considered model. Boundary input is an important characteristic for
Meng‐Zhen Ren +2 more
doaj +1 more source
On controlled linear diffusions with delay in a model of optimal advertising under uncertainty with memory effects [PDF]
We consider a class of dynamic advertising problems under uncertainty in the presence of carryover and distributed forgetting effects, generalizing a classical model of Nerlove and Arrow.
Gozzi, Fausto +2 more
core +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Synchronization of coupled neutral-type neural networks with jumping-mode-dependent discrete and unbounded distributed delays [PDF]
This is the post-print version of the Article. The official published version can be accessed from the links below - Copyright @ 2013 IEEE.In this paper, the synchronization problem is studied for an array of N identical delayed neutral-type neural ...
Liang, J, Liu, X, Liu, Y, Wang, Z
core +2 more sources
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Blow up of Coupled Nonlinear Klein-Gordon System with Distributed Delay, Strong Damping, and Source Terms [PDF]
This present work deals with the blow up of the coupled Klein-Gordon system with strong damping, distributed delay, and source terms, under suitable conditions.
Djamel Ouchenane +4 more
openaire +2 more sources
Traffic Engineering in G-MPLS networks with QoS guarantees [PDF]
In this paper a new Traffic Engineering (TE) scheme to efficiently route sub-wavelength requests with different QoS requirements is proposed for G-MPLS networks.
Battiti, Roberto, Salvadori, Elio
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source

