Results 51 to 60 of about 848,892 (315)

Long-Term Clock Synchronization in wireless sensor networks with arbitrary delay distributions [PDF]

open access: yes2012 IEEE Global Communications Conference (GLOBECOM), 2012
Clock synchronization is a crucial issue in the operation of wireless sensor networks. Although the existing synchronization algorithms under linear clock model assumptions perform well for short periods, they will become problematic for applications with long-term requirements.
null Wanlu Sun   +3 more
openaire   +1 more source

Exponential input‐to‐state stability of delay reaction‐diffusion systems

open access: yesIET Control Theory & Applications, 2021
This brief paper considers the exponential input‐to‐state stability (EISS) for delay reaction‐diffusion systems (DRDSs). The distributed input and boundary input are both included in the considered model. Boundary input is an important characteristic for
Meng‐Zhen Ren   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

A distributed networked approach for fault detection of large-scale systems [PDF]

open access: yes, 2016
Networked systems present some key new challenges in the development of fault diagnosis architectures. This paper proposes a novel distributed networked fault detection methodology for large-scale interconnected systems.
Boem, F   +4 more
core   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

open access: yesFEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó   +7 more
wiley   +1 more source

Traffic Engineering in G-MPLS networks with QoS guarantees [PDF]

open access: yes, 2003
In this paper a new Traffic Engineering (TE) scheme to efficiently route sub-wavelength requests with different QoS requirements is proposed for G-MPLS networks.
Battiti, Roberto, Salvadori, Elio
core  

Network Formation Games Among Relay Stations in Next Generation Wireless Networks

open access: yes, 2011
The introduction of relay station (RS) nodes is a key feature in next generation wireless networks such as 3GPP's long term evolution advanced (LTE-Advanced), or the forthcoming IEEE 802.16j WiMAX standard. This paper presents, using game theory, a novel
Başar, Tamer   +4 more
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

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