Results 111 to 120 of about 3,609,462 (370)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

High-Throughput Computing on High-Performance Platforms: A Case Study

open access: yes, 2017
The computing systems used by LHC experiments has historically consisted of the federation of hundreds to thousands of distributed resources, ranging from small to mid-size resource.
Angius, Alessio   +8 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The Beginnings of a Small Ethiopian, Organizational Leadership Library Collaborative

open access: yes, 2007
An Azusa Pacific University Reference Librarian describes the logistical, cultural, and spiritual aspects of a library building journey to Ethiopia which brought the means for a successful implementation of a new small academic library to hundreds of ...
Shimazu Yee, Evelyn
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Challenges, opportunities and strategies of distributed leadership in managing environmental education curriculum in South African secondary schools

open access: yesInternational Journal of Educational Management and Development Studies
The study explores the application of distributed leadership in managing environmental education curricula in South African secondary schools. Adopting a qualitative case study design, data was collected through semi-structured interview and observations
Nonkanyiso Pamella Shabalala
doaj   +1 more source

Distributing Leadership [PDF]

open access: yes, 2009
{Excerpt} The prevailing view of leadership is that it is concentrated or focused. In organizations, this makes it an input to business processes and performance—dependent on the attributes, behaviors, experience, knowledge, skills, and potential of the ...
Serrat, Olivier
core   +1 more source

Values-Based Network Leadership in an Interconnected World [PDF]

open access: yes, 2017
This paper describes values-based network leadership conceptually aligned to systems science, principles of networks, moral and ethical development, and connectivism. Values-based network leadership places importance on a leader\u27s repertoire of skills
Calongne, Cynthia   +5 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The impact of deans’ distributed leadership on university teachers’ job performance: the mediating role of job satisfaction

open access: yesCogent Education
This study investigates how deans’ distributed leadership influences university teachers’ job performance in Jiangsu, China, emphasizing the mediating role of job satisfaction. A structured questionnaire survey collected data from 470 university teachers,
Hua Yu   +3 more
doaj   +1 more source

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