Results 101 to 110 of about 819,025 (284)

The impact of deans’ distributed leadership on university teachers’ job performance: the mediating role of job satisfaction

Cogent Education
This study investigates how deans’ distributed leadership influences university teachers’ job performance in Jiangsu, China, emphasizing the mediating role of job satisfaction. A structured questionnaire survey collected data from 470 university teachers,
Hua Yu, Aida Hanim A. Hamid, Jamalul Lail Abdul Wahab, Mohd Izwan Mahmud   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Distributed leadership, team working and service improvement in healthcare [PDF]

, 2015
Purpose– The purpose of this paper is to analyse the introduction of distributed leadership and team working in a therapy department in a healthcare organisation and to explore the factors that enabled the introduction to be successful.Design/methodology/
Boak, George, Brown, Louise, Dickens, Victoria, Newson, Annalisa   +3 more
core   +1 more source

Distributed Digital Leadership in Grundschulen

Medienimpulse
Die vorliegende Delphi-Studie untersucht zentrale Handlungsstrategien für digitale Schulentwicklungsprozesse in Grundschulen unter der theoretischen Perspektive des Distributed Digital Leadership (DDL).
Nina Autenrieth
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Att närvara där det händer – det pedagogiska ledarskapets betydelse för att leda lärares återkopplingsarbete

Nordic Studies in Education
This article discusses instructional leadership and its implications for professional development of formative assessment conducted by teachers. Theories of instructional leadership claim that distributed leadership is seen as a strategy for principals ...
Anna Sarri Krantz
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Distributing leadership in a day care setting

Journal of Early Childhood Education Research, 2016
The latest leadership theories require leadership to be distributed, but there is little evidence of how the distribution is made in practice, particularly in the context of early childhood education.
Leena Halttunen
doaj