Results 81 to 90 of about 2,576,787 (284)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Emergent, distributed, and orchestrated Understanding leadership through frame analysis

open access: yes, 2019
Leadership scholars are beginning to understand leadership as a distributed phenomenon, produced in interaction and emerging in social situations. Although this perspective has contributed to understanding leadership processes in more detail, it has also
Alvehus, Johan,, Lund University.
core   +1 more source

Distributed Leadership as a Path to Organizational Commitment: The Case of a Lebanese School [PDF]

open access: yes, 2020
This study explores distributed leadership in school characterized by high teacher organizational commitment using case study research. Leadership is distributed in formal and informal manners.
Berjaoui, Roula Rafic   +1 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Educational leadership for international partnerships between New Zealand and east Asian Chinese higher education institutions [PDF]

open access: yes, 2009
This study examines how higher education leaders in different socio-cultural contexts are involved in the practice of distributed leadership in international partnerships.
Ho, Ai-Hsin
core  

Degrees of distribution: Towards an understanding of variations in the nature of distributed leadership in schools

open access: yes, 2007
The research reported on in this article explores how degrees of leadership distribution in schools might be differentiated. Data were collected from ten schools - eight primary and two secondary schools - which were identified as exhibiting 'good ...
Philip A. Woods   +3 more
core   +1 more source

The Chain Mediating Role of Teachers’ Job Stress in the Influence of Distributed School Leadership on Job Satisfaction: Evidence from China, the United States, England, and Australia

open access: yesBehavioral Sciences
Distributed leadership has been shown to improve teacher job satisfaction and reduce teacher job stress. However, few studies have thoroughly explored the indirect effects of distributed leadership on increasing the teachers’ burden in school ...
Jian Li, Eryong Xue, Yuxuan Liu
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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