Results 171 to 180 of about 3,609,462 (370)
Socially Focused, Situationally Driven Practice: A Study of Distributed Leadership among School Principals and Counselors [PDF]
, 2007 Matthew Militello, Chris Janson
openalex +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
A study into the practice of distributed leadership within the post-primary school sector in Ireland
, 2019 Niall McVeigh
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Educational Technology & Society, 2019 The study looked into how school partnership generates benefit. It aimed to identify the structures of partnership among collaborating schools and to examine elements that can contribute to sustainable e-Learning development.
Siu Cheung Kong
doaj
SAGE OpenThis study examines the role of distributed leadership behaviours in the empirical relationship between school principals’ commitment and trust with their well-being.
Hatice Turan Bora +2 more
doaj +1 more source
Competencies Model of a Leader In a Healthcare Organization: International Experience of Distributed Leadership Implementation [PDF]
, 2016 О. В. Куделина
openalex +1 more source
Complexity and leadership in teacher professional development : the case of the National Centre for Excellence in the Teaching of Mathematics [PDF]
There has been considerable interest in the teaching of mathematics over the last two decades, both internationally and in the UK. This has led to a number of government sponsored interventions in both curriculum and teacher professional development. The
Boylan, Mark +2 more
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source