Results 121 to 130 of about 1,173,521 (350)

Mitigating the Effects of Sensor and Actuator Attacks in Uncertain Networked Multiagent Systems

open access: yesAerospace
This paper presents a novel distributed robust adaptive control architecture for leader–follower networked multiagent systems with static undirected communication graph topologies to mitigate the effects of time-varying sensor and actuator attacks, and ...
Dhruva Venkat   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The effects of internal resonances in vibration isolators under absolute velocity feedback control

open access: yes, 2007
Conventional vibration isolators are usually assumed to be massless for modelling purposes, which tends to overestimate the isolator performance because the internal resonances (IRs) due to the inertia of the isolator are neglected.
Brennan, Mike   +3 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A Survey on Parameter Server Architecture: Approaches for Optimizing Distributed Centralized Learning

open access: yesIEEE Access
Deep learning has emerged as a cornerstone technology across various domains, from image classification to natural language processing. However, the computational and data demands of training large-scale neural networks pose significant challenges ...
Nikodimos Provatas   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Adaptive prescribed performance control for wave equations with dynamic boundary and multiple parametric uncertainties

open access: yesAIMS Mathematics
In modern engineering, the dynamics of many practical problems can be described by hyperbolic distributed parameter systems. This paper is devoted to the adaptive prescribed performance control for a class of typical uncertain hyperbolic distributed ...
Zaihua Xu , Jian Li
doaj   +1 more source

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